In 1968, Roxanne Dunbar-Ortiz became a founding member of the early women's liberation movement. Along with a small group of dedicated women, she produced the seminal journal series, No More Fun and Games. Her group, Cell 16 occupied the radical fringe of the growing movement, considered too outspoken and too outrageous by mainstream advocates for women's rights.

Dunbar-Ortiz was also a dedicated anti-war activist and organizer throughout the 1960s and 1970s. During the war years she was a fiery, indefatigable public speaker on issues of patriarchy, capitalism, imperialism, and racism. She worked in Cuba with the Venceremos Brigade, and formed associations with other revolutionaries across the spectrum of radical and underground politics, including the SDS, the Weather Underground, the Revolutionary Union, and the African National Congress. But unlike the majority of those in the New Left—young white men from solidly middle-class suburban families—Dunbar-Ortiz grew up poor, female, and part-Indian in rural Oklahoma, and she often found herself at odds not only with the ruling class but also with the Left and with the women's movement.

Dunbar-Ortiz's odyssey from dust-bowl poverty to the urban radical fringes of the New Left gives a working-class, feminist perspective on a time and a movement which forever changed American society.