Mitch and Amy is a children's novel by Beverly Cleary, illustrated by George Porter, Bob Marstall, Alan Tiegreen, and Tracy Dockray, first published in 1967.

The story follows the escapades of the fraternal Huff twins, Mitch and Amy, in Berkeley, California. Although the book was written in the late 1960s, the book stays true to Cleary's penchant for making the stories relevant regardless of the time period.