New York, 1993. Alice Culvert is a caring wife, a doting new mother, a loyal friend, and a soulful artist, a fashion designer who wears a baby carrier and haute couture with equal aplomb. In their loft in Manhattan's gritty Meatpacking District, Alice and her husband, Oliver, are raising their infant daughter, Doe, delighting in the wonders of early parenthood. Their life together feels so vital and full of promise, which makes Alice's sudden cancer diagnosis especially staggering. In the span of a single day, the couple's focus narrows to the basic question of her survival. Though they do their best to remain brave, each faces enormous pressure: Oliver tries to navigate a labyrinthine healthcare system and handle their mounting medical bills; Alice tries to be hopeful as her body turns against her. Bracing themselves for the unthinkable, they must confront the new realities of their marriage, their strengths as partners and flaws as people, how to nourish love against all odds, and what it means to truly care for another person.