Theory and mathematical methods in bioinformatics

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Theory and mathematical methods in bioinformatics

"This monograph addresses, in a systematic and pedagogical manner, the mathematical methods and the algorithms required to deal with the molecularly based problems of bioinformatics. The book will be useful to students, research scientists and practitioners of bioinformatics and related fields, especially those who are interested in the underlying mathematical methods and theory. Among the methods presented in the book, prominent attention is given to pair-wise and multiple sequence alignment algorithms, stochastic models of mutations, modulus structure theory and protein configuration analysis. Strong links to the molecular structures of proteins, DNA and other biomolecules and their analyses are developed. In particular, for proteins an in-depth exposition of secondary structure prediction methods should be a valuable tool in both molecular biology and in applications to rational drug design. The book can also be used as a textbook and for this reason most of the chapters include exercises and problems at the level of a graduate program in bioinformatics."--Jacket.

Publish Date
Publisher
Springer
Language
English
Pages
445

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Previews available in: English

Edition Availability
Cover of: Theory and mathematical methods in bioinformatics
Theory and mathematical methods in bioinformatics
2008, Springer
electronic resource / in English

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Book Details


Table of Contents

Pt. I. Mutations and Alignments. Introduction
Stochastic Models of Mutations and Structural Analysis
Modulus Structure Theory
Super Pairwise Alignment
Multiple Sequence Alignment
Network Structures of Multiple Sequences Induced by Mutation
Alignment Space
Pt. II. Protein Configuration Analysis. Background Information Concerning the Properties of Proteins
Informational and Statistical Iterative Analysis of Protein Secondary Structure Prediction
Three-Dimensional Structure Analysis of the Protein Backbone and Side Chains
Alignment of Primary and Three-Dimensional Structures of Proteins
Depth Analysis of Protein Spatial Structure
Analysis of the Morphological Features of Protein Spatial Structure
Semantic Analysis for Protein Primary Structure.

Edition Notes

Includes bibliographical references (p. [433]-439) and index.

Description based on print version record.

Published in
Berlin
Series
Biological and medical physics, biomedical engineering, Biological and medical physics, biomedical engineering

Classifications

Dewey Decimal Class
572.80285
Library of Congress
QH324.2 .S54 2008eb, QH301-705T57-57.97QH, QH324.2 .S54 2008, QH301-705

The Physical Object

Format
[electronic resource] /
Pagination
1 online resource (xvi, 445 p.) :
Number of pages
445

Edition Identifiers

Open Library
OL25544376M
Internet Archive
theorymathematic00shen
ISBN 10
3540748911, 3540748903
ISBN 13
9783540748915, 9783540748908
LCCN
2007939206
OCLC/WorldCat
233973499

Work Identifiers

Work ID
OL16938829W

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