Analyzing Criminal Minds: Forensic Investigative Science for the 21st Century explores new and emerging approaches to a perennially fascinating subject. Author Don Jacobs looks at 10 tools and products that have revolutionized the discipline, explaining how modern criminal mind analysis incorporates advances in criminal and forensic psychology, forensic neuropsychology, brain imaging, adolescent neurobiology, criminal profiling, and brain fingerprinting, as well as research into the paralimbic brain system and the impact of the "DANE" brain upon adolescent and young adult behavior.

Twenty-three characteristics shared by jailed violent criminals are analyzed and considered in terms of neuropsychology and developmental psychology. The book also probes psychopathy in its various degrees, in children, adolescents, and adults, and explains a controversial but increasingly accepted theory that psychopathy is a "natural" outgrowth of evolution, describing how this "natural" psychopathy can become a condition typified by violent, sadistic, and irreversible personality disorder.