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Table of Contents
The discovery and development of sunitinib (SU11248)
Tykerb discovery : a dual EGFR and erbB2 tyrosine kinase inhibitor
Discovery of pazopanib, a potent pan vascular endothelial growth factor inhibitor in clinical development
The road to ABT-869, a multi-targeted receptor tyrosine kinase inhibitor
Discovery of motesanib
The discovery of brivanib alaninate, a dual vascular endothelial growth factor and fibroblast growth factor receptor inhibitor
Structure-based design and characterization of axitinib
The road to PD0325901 and beyond : the MEK inhibitors quest
The discovery of allosteric MEK inhibitors
The discovery of MK-0457 (VX-680)
Discovery of PHA-739358
The discovery of AZD1152 : a selective inhibitor of aurora B kinase with potent anti-tumor activity
Case study of aurora A inhibitor MLN8054
The discovery of GSK461364a
Pharmacogenomics of dasatinib
Practical use of computational chemistry in kinase drug discovery
Approaches to kinase homology modeling : successes and consideration for the structural kinome
Fragment-based drug discovery of kinase inhibitors
Protein kinase structural biology : methods and strategies for targeted drug discovery.
Edition Notes
Includes index.
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