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Subjects
Microelectromechanical systems, Chemical laboratories, Biomedical engineering, Electronic equipment, Labs on a chip, Nanotechnology, Microchemistry, Lab-On-A-Chip Devices, Microchip Analytical Procedures, Microtechnology, Biosensing Techniques, Micro-Electrical-Mechanical Systems, Microsystèmes électromécaniques, Chimie, Laboratoires, Équipement électronique, Génie biomédical, Laboratoires sur puces, Nanotechnologie, Microchimie, TECHNOLOGY & ENGINEERING, Electronics, Microelectronics, DigitalShowing 1 featured edition. View all 1 editions?
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Lab-on-a-chip: techniques, circuits, and biomedical applications
2010, Artech House
in English
1596934182 9781596934184
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Book Details
Table of Contents
1. Introduction to Lab-on-a-Chip
1.1. History
1.2. Parts and Components of Lab-on-a-Chip
1.2.1. Electric and Magnetic Actuators
1.2.2. Electrical Sensors
1.2.3. Thermal Sensors
1.2.4. Optical Sensors
1.2.5. Microfluidic Chambers
1.3. Applications of Lab-on-a-Chip
1.4. Advantages and Disadvantages of Lab-on-a-Chip
References
2. Cell Structure, Properties, and Models
2.1. Cell Structure
2.1.1. Prokaryotic Cells
2.1.2. Eukaryotic Cells
2.1.3. Cell Components
2.2. Electromechanics of Particles
2.2.1. Single-Layer Model
2.2.2. Double-Layer Model
2.3. Electrogenic Cells
2.3.1. Neurons
2.3.2. Gated Ion Channels
2.3.3. Action Potential
References
3. Cell Manipulator Fields
3.1. Electric Field
3.1.1. Uniform Electric Field (Electrophoresis)
3.1.2. Nonuniform Electric Field (Dielectrophoresis)
3.2. Magnetic Field
3.2.1. Nonuniform Magnetic Field (Magnetophoresis)
3.2.2. Magnetophoresis Force (MAP Force)
References
4. Metal-Oxide Semiconductor (MOS) Technology Fundamentals
4.1. Semiconductor Properties
4.2. Intrinsic Semiconductors
4.3. Extrinsic Semiconductor
4.3.1. N-Type Doping
4.3.2. P-Type Doping
4.4. MOS Device Physics
4.5. MOS Characteristics
4.5.1. Modes of Operation
4.6. Complementary Metal-Oxide Semiconductor (CMOS) Device
4.6.1. Advantages of CMOS Technology
References
5. Sensing Techniques for Lab-on-a-Chip
5.1. Optical Technique
5.2. Fluorescent Labeling Technique
5.3. Impedance Sensing Technique
5.4. Magnetic Field Sensing Technique
5.5. CMOS AC Electrokinetic Microparticle Analysis System
5.5.1. Bioanalysis Platform
5.5.2. Experimental Tests
References
6. CMOS-Based Lab-on-a-Chip
6.1. PCB Lab-on-a-Chip for Micro-Organism Detection and Characterization
6.2. Actuation
6.3. Impedance Sensing
6.4. CMOS Lab-on-a-Chip for Micro-Organism Detection and Manipulation
6.5. CMOS Lab-on-a-Chip for Neuronal Activity Detection
6.6. CMOS Lab-on-a-Chip for Cytometry Applications
6.7. Flip-Chip Integration
References
7. CMOS Electric-Field-Based Lab-on-a-Chip for Cell Characterization and Detection
7.1. Design Flow
7.2. Actuation
7.3. Electrostatic Simulation
7.4. Sensing
7.5. The Electric Field Sensitive Field Effect Transistor (eFET)
7.6. The Differential Electric Field Sensitive Field Effect Transistor (DeFET)
7.7. DeFET Theory of Operation
7.8. Modeling the DeFET
7.8.1. A Simple DC Model
7.8.2. SPICE DC Equivalent Circuit
7.8.3. AC Equivalent Circuit
7.9. The Effect of the DeFET on the Applied Electric Field Profile
References
8. Prototyping and Experimental Analysis
8.1. Testing the DeFET
8.1.1. The DC Response
8.1.2. The AC (Frequency) Response
8.1.3. Other Features of the DeFET
8.2. Noise Analysis
8.2.1. Noise Sources
8.2.2. Noise Measurements
8.3. The Effect of Temperature and Light on DeFET Performance
8.4. Testing the Electric Field Imager
8.4.1. The Response of the Imager Under Different Environments
8.4.2. Testing the Imager with Biocells
8.5. Packaging the Lab-on-a-Chip
References
9. Readout Circuits for Lab-on-a-Chip
9.1. Current-Mode Circuits
9.2. Operational Floating Current Conveyor (OFCC)
9.2.1. A Simple Model
9.2.2. OFCC with Feedback
9.3. Current-Mode Instrumentation Amplifier
9.3.1. Current-Mode Instrumentation Amplifier (CMIA) Based on CCII
9.3.2. Current-Mode Instrumentation Amplifier Based on OFCC
9.4. Experimental and Simulation Results of the Proposed CMIA
9.4.1. The Differential Gain Measurements
9.4.2. Common-Mode Rejection Ratio Measurements
9.4.3. Other Features of the Proposed CMIA
9.4.4. Noise Results
9.5. Comparison Between Different CMIAs
9.6. Testing the Readout Circuit with the Electric Field Based Lab-on-a-Chip
References
10. Current-Mode Wheatstone Bridge for Lab-on-a-Chip Applications
10.1. Introduction
10.2. CMWB Based on Operational Floating Current Conveyor
10.3. A Linearization Technique Based on an Operational Floating Current Conveyor
10.4. Experimental and Simulation Results
10.4.1. The Differential Measurements
10.4.2. Common-Mode Measurements
10.5. Discussion
References
11. Current-Mode Readout Circuits for the pH Sensor
11.1. Introduction
11.2. Differential ISFET-Based pH Sensor
11.2.1. ISFET-Based pH Sensor
11.2.2. Differential ISFET Sensor
11.3. pH Readout Circuit Based on an Operational Floating Current Conveyor
11.3.1. Simulation Results
11.4. pH Readout Circuit Using Only Two Operational Floating Current Conveyors
11.4.1. Simulation Results
References.
Edition Notes
Includes bibliographic references and index.
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- Created October 20, 2011
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