The focus of this text is the two-part approach that any physician treating head and neck cancer patients must follow: maximize the chance for a cure while maintaining a strong emphasis on quality of life. Coverage begins with reviews of the molecular biology and other basic science aspects of these cancers. The second section presents general principles of patient management, while the third and major section offers detailed guidelines for surgical and non-surgical management of cancers at specific anatomic sites. The concluding section explores future directions in head and neck oncology, including radiation therapy, chemotherapy, gene and biological therapy, ethical considerations, outcomes research, and cost analysis. More than 1,600 illustrations complement the text. The Second Edition integrates a focus on technique into each site-specific chapter.