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Drug-DNA interaction protocols
2010, Humana Press, Springer Science+Business Media
in English
- 2nd ed.
1603274170 9781603274173
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Book Details
Table of Contents
1. Quantitative analysis of small molecule-nucleic acid interactions with a biosensor surface and surface plasmon resonance detection / Yang Liu and W. David Wilson
2. Thermal melting studies of ligand DNA interactions / Aurore Guédin, Laurent Lacroix, and Jean-Louis Mergny
3. Circular and linear dichroism of drug-DNA systems / Alison Rodger
4. Drug binding to DNA-RNA hybrid structures / Richard T. Wheelhouse and Jonathan B. Chaires
5. Quantification of binding data using capillary electrophoresis / Fitsumbirhan Araya, Graham G. Skellern, and Roger D. Waigh
6. Determination of equilibrium association constants of ligand-DNA complexes by electrospray mass spectrometry / Valérie Gabelica
7. Detection of adriamycin-DNA adducts by accelerator mass spectrometry / Kate Coldwell ... [et al.]
8. Molecular modelling methods to quantitate drug-DNA interactions / Hao Wang and Charles A. Laughton
9. Application of anomalous diffraction methods to the study of DNA and DNA-complexes / Derrick Watkins ... [et al.]
10. DNase I footprinting / Antonia S. Cardew and Keith R. Fox
11. Methods to characterize the effect of DNA-modifying compounds on nucleosomal DNA / Vidya Subramanian ... [et al.]
12. REPSA: combinatorial approach for identifying preferred drug-DNA binding sequences / Michael W. Van Dyke
13. In vitro transcription assay for resolution of drug-DNA interactions at defined DNA sequences / Benny J. Evison, Don. R. Phillips, and Suzanne M. Cutts
14. In virtro footprinting of promoter regions within supercoiled plasmid DNA / Daekyu Sun
15. Topoisomerase I-mediated DNA relaxation as a tool to study intercalation of small molecules and supercoiled DNA / Paul Peixoto ... [et al.]
16. A high-throughput assay for DNA topoisomerases and other enzymes based on DNA triplex formation / Matthew R. Burrell, Nicolas P. Burton and Anthony Maxwell
17. Measurement of DNA interstrand crosslinking in individual cells using the single cell gel electrophoresis (Comet) assay / Victoria J. Spanswick, Janet M. Hartley, and John A. Hartley
18. Measurement of DNA interstrand crosslinking in naked DNA using Gel-based methods / Konstantinous Kiakos, Janet M. Hartley, and John A. Hartley
19. An evaluation cascade for G-quadruplex telomere targeting agents in human cancer cells / Mekala Gunaratnam and Stephen Neidle.
Edition Notes
Includes bibliographical references and index.
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- Created July 29, 2011
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