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This introduction to computational molecular biology will help programmers and biologists learn the skills needed to start work in this important, expanding field. The author explains many of the basic computational problems and gives concise, working programs to solve them in the Perl programming language. With minimal prerequisites, the author explains the biological background for each problem, develops a model for the solution, then introduces the Perl concepts needed to implement the solution. The book covers pairwise and multiple sequence alignment, fast database searches for homologous sequences, protein motif identification, genome rearrangement, physical mapping, phylogeny reconstruction, satellite identification, sequence assembly, gene finding, and RNA secondary structure. The concrete examples and step-by-step approach make it easy to grasp the computational and statistical methods, including dynamic programming, branch-and-bound optimization, greedy methods, maximum likelihood methods, substitution matrices, BLAST searching, and Karlin-Altschul statistics. Perl code is provided on the accompanying CD.
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Previews available in: English
Subjects
Bioinformatics, Computer Technology, Data processing, Molecular biology, Nonfiction, Perl (Computer program language), Informatique, Perl (Langage de programmation), Computational Biology, COMPUTERS, Molekulare Bioinformatik, Perl (Programmiersprache), Biologie moléculaire, Bio-informatiqueEdition | Availability |
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1
Genomic Perl: From Bioinformatics Basics to Working Code
2012, Cambridge University Press
in English
1139164767 9781139164764
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2 |
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3
Genomic Perl: from bioinformatics basics to working code
2003, Cambridge University Press
in English
052180177X 9780521801775
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4
Genomic Perl: From Bioinformatics Basics to Working Code
2002, Cambridge University Press
in English
051107185X 9780511071850
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5
Genomic Perl: From Bioinformatics Basics to Working Code
July 15, 2002, Cambridge University Press
Hardcover
in English
- Har/Cdr edition
052180177X 9780521801775
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6
Genomic Perl: From Bioinformatics Basics to Working Code
2002, Cambridge University Press
in English
1139147102 9781139147101
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Book Details
Edition Notes
Includes bibliographical references (p. 318-323) and index.
System requirements: ISO 9660 format for Macintosh, Windows, UNIX, and LINUX.
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History
- Created September 20, 2008
- 11 revisions
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December 8, 2020 | Edited by MARC Bot | import existing book |
August 19, 2020 | Edited by ImportBot | import existing book |
December 29, 2019 | Edited by ImportBot | import existing book |
June 30, 2019 | Edited by MARC Bot | import existing book |
September 20, 2008 | Created by ImportBot | Imported from Western Washington University MARC record |