This volume presents the work of distinguished investigators who have conducted major studies on the role of eicosanoids in inflammation. The book provides an informative appraisal of the current state of the art in leukotriene and inflammation research, integrating new basic science concepts and clinical findings. The primary focus of the book is on the evidence that leukotrienes represent a group of mediators that contribute significantly to the pathobiology of asthma and play a role in other inflammatory disorders. The information presented in this volume is of vital importance to pharmacologists, biochemists, and physiologists, as well as to clinicians treating patients with asthma and other inflammatory diseases.