This volume is dedicated to Harold Widom, a distinguished mathematician and renowned expert in the area of Toeplitz, Wiener-Hopf and pseudodifferential operators, on the occasion of his sixtieth birthday. The book opens with biographical material and a list of the mathematician's publications, this being followed by two papers based on Toeplitz lectures which he delivered at Tel Aviv University in March, 1993. The rest of the book consists of a selection of papers containing some recent achievements in the following areas: Szegö-Widom asymptotic formulas for determinants of finite sections of Toeplitz matrices and their generalizations, the Fisher-Hartwig conjecture, random matrices, analysis of kernels of Toeplitz matrices, projectional methods and eigenvalue distribution for Toeplitz matrices, the Fredholm theory for convolution type operators, the Nehari interpolation problem with generalizations and applications, and Toeplitz-Hausdorff type theorems. The book will appeal to a wide audience of pure and applied mathematicians.