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This text presents a general introduction to soft tissue biomechanics. One of its primary goals is to introduce basic analytical, experimental and computational methods. In doing so, it enables readers to gain a relatively complete understanding of the biomechanics of the heart and vasculature.
Cardiovascular Solid Mechanics: Cells, Tissues, and Organs is a vital resource for courses on cardiovascular solid mechanics or soft tissue biomechanics. Focusing on the response of the heart and blood vessels to mechanical loads from the perspective of nonlinear solid mechanics, its primary goal is to integrate basic analytical, experimental, and computational methods to offer a more complete understanding of the underlying mechanobiology. While dealing primarily with cardiovascular mechanics, both the fundamental methods and many of the specific results are applicable to many different soft tissues, making this book an excellent general introduction to soft tissue biomechanics overall. Divided into three parts, Cardiovascular Solid Mechanics presents a practical and rational approach to biomechanics.
Part I, Foundations, briefly reviews historical points of interest, basic molecular and cell biology, histology, and an overview of soft tissue mechanics. In order to provide not only a working framework, but also to give key references for those who wish to develop and extend biomechanics, included are mathematical preliminaries and salient results from continuum mechanics, finite elasticity, experimental mechanics, and finite elements.
Part II, Vascular Mechanics, reviews the anatomy, histology, and physiology of arteries, illustrating and discussing constitutive formulations and stress analyses for healthy mature arteries. Considerable attention is given to the concept of residual stress and the mechanics of a number of vascular disorders, including atherosclerosis, aneurysms, and hypertension, as well as the mechanics of popular endovascular therapies such as balloon angioplasty.
Part III, Cardiac Mechanics, reviews the requisite anatomy, histology, physiology, and pathology, and discusses the constitutive relations and stress analyses in the normal, mature heart. Finally, the book points the reader to areas of study that require more advanced theoretical, experimental, and computational methods, such as electromechanics, thermomechanics, mixture theory analysis of solid-fluid coupling, and damage mechanics. This book is designed as a text for an upper-division course on cardiovascular solid mechanics but will also serve as a good introduction to soft tissue biomechanics. Exercises at the end of each chapter will clarify complex concepts for both students and more experienced readers. Clinicians, life scientists, engineers, and mathematicians will also find this an invaluable guide, with concise and practical chapters, all of which are amply referenced. Cover illustration: Schema of a developing pathology of the arterial wall under mechanical stress.
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Edition | Availability |
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1
Cardiovascular Solid Mechanics: Cells, Tissues, and Organs
2013, Springer London, Limited
in English
038721576X 9780387215761
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2
Cardiovascular Solid Mechanics: Cells, Tissues, and Organs
Dec 01, 2010, Springer, Springer New York
paperback
1441928979 9781441928979
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3
Cardiovascular Solid Mechanics: Cells, Tissues, and Organs
January 8, 2002, Springer
Hardcover
in English
0387951687 9780387951683
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As a specialty area within biomechanics, cardiovascular solid mechanics seeks to increase our understanding of the physiology and pathophysiology of the heart and vasculature, and to improve the requisite diagnostic and therapeutic capabilities. Our approach is base on the *continuum hypothesis*, thus we assume that characteristic length scales of the microstructure are much smaller than characteristic length scales of the overall problem of interest (e.g., a vascular smooth muscle cell is orders of magnitude smaller than the thickness of the arterial wall). Given this assumption, we can define locally averaged properties at each point in the body and thereby define physical quantities of interest using continuous functions.
This excerpt outlines the scope of the monograph and the general investigative approach used.
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