The educational demands of orthodontics, which demands the integration of the best research evidence with the clinician's expertise and the patient's unique values and circumstances. This land-mark text is the first to be devoted to the methodology, principles and practice of evidence-based practice in orthodontics. It aims to serve as a reference for those wishing to understand the principles of evidence-based practice including the foundation for clinical study design, epidemiology and the statistical inferences from data. The ability to define a search strategy from established databases and to identify relevant clinical and translational research in the scientific published literature requires a new approach in orthodontic education. An contemporary approach to those strategies in clinical orthodontic practice. The growing ability to translate critical appraisals of evidence into clinical practice and evaluate clinical evidence for its validity and potential usefulness requires an understanding of basic elements in epidemiology and biostatistics. This book provides its readers with a cogent, clear resource with which to navigate and understand this important subject area. It provides students and practitioners of orthodontics with an indispensible guide to this vital tenet of education, research, and clinical practice.