This book constitutes the refereed proceedings of the 16th International Conference on Speech and Computer, SPECOM 2014, held in Novi Sad, Serbia. The 56 revised full papers presented  together with 3 invited talks were carefully reviewed and selected from 100 initial submissions. It is a conference with long tradition that attracts researchers in the area of computer speech processing (recognition, synthesis, understanding etc.) and related domains (including signal processing, language and text processing, multi-modal speech processing or human-computer interaction for instance).