The booklet summarizes the history of trans and intersex pathologization, healthcare access and activism and highlights the processes undertaken by the World Health Organization (WHO) in updating its International Classification of Diseases (ICD). ICD 10, adopted in 1990, classifies trans and gender-diverse persons under the chapter on mental and behavioural disorders, while the various categories of intersex conditions have been placed in a wide range of chapters focusing on physical and genetic disorders. It is this pathologization, psycho-pathologization and cis-normative language which Iranti and groups like it have strongly campained against, as it reinforces stereotypes and more often than not results in inhumane corrective procedures. ... The toolkit further outlines the work that still needs to be done with regard to ICD 11 and other medical resources pertaining to transgender and intersex healthcare, and will navigate the reader easily through the various aspects of transgender healthcare and the importance of depathologising trans identities in order to improve the standard of living for trans and intersex persons both globally and in Africa. --