The books is the outcome of an interdisciplinary and interinstitutional research work carried out by the Alianza de Universidades para el Desarrollo Urbano Regional con Equidad (Alliance of Universities for Regional Urban Development with Equity), constituted by the Universidad Autónoma de Occidente, the Universidad ICESI, the Pontificia Universidad Javeriana-Cali, the Universidad de San Buenaventura-Cali and the Universidad del Valle with the Support of the Ford Foundation. The authors analyze an area of 28 municipalities of two departments; 14 of the Cauca`s north and 14 of Valle del Cauca south, with main pole of development the city of Cali, result a process of long duration from the XVIII century. The dimensions analyzed from the 1960s are the following variables: characterization of the municipalities according to their degree of urbanity-rurality; ethnic-racial composition of the 2005 census; rates of population growth of the municipalities of the region between 1964 and 2005, and 2016 with demographic projections; and lifelong migration and recent in 2005. The methodology is descriptive statistics with cartographic support on the space analyzed, according to the aforementioned variables, identifying receiving and expelling municipalities of the whole life and recent population, on a regional and national scale. This allows to delimit a pluri-ethnic and pluri-racial region of municipalities between the departments of Valle del Cauca and Cauca as hinterland of greater proximity to the city of Cali.