Assessing ocular toxicology in laboratory animals

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Assessing ocular toxicology in laboratory ani ...
Andrea B. Weir, Collins, Marga ...
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September 12, 2021 | History

Assessing ocular toxicology in laboratory animals

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Ocular toxicity is routinely assessed in toxicology studies conducted for regulatory purposes. Ocular anatomy and physiology and the assessment of ocular toxicity itself can be challenging to scientists involved in the safety assessment of pharmaceuticals, pesticides and other agents. Anatomical and physiological differences between species can impact the nature of ocular effects observed following intended or unintended exposure of ocular tissues to xenobiotics. Ocular Toxicity in Laboratory Animals provides a concise reference addressing ocular anatomy and physiology across species that will enhance the design and interpretation of toxicology studies conducted for regulatory purposes. The book provides an overview of routine and advanced techniques that are used to assess ocular toxicity including slit lamp biomicroscopy, indirect ophthalmoscopy, electrophysiology and imaging methods for the anterior and posterior segments of the eye. Additionally, the book defines the regulatory expectations for pharmaceuticals intended to treat ocular diseases and for other non-pharmaceutical regulated chemicals. With contributions from experts in the field, Ocular Toxicity in Laboratory Animals is an authoritative, accessible guide for toxicologists and other scientists involved in conducting toxicology studies for regulatory purposes and/or reviewing data from such studies.

Publish Date
Language
English
Pages
319

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Edition Availability
Cover of: Assessing ocular toxicology in laboratory animals
Assessing ocular toxicology in laboratory animals
2013, Humana Press (some color)
in English

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Book Details


Table of Contents

Comparative Ocular Anatomy in Commonly Used Laboratory Animals -- Mark Vézina
Assessment of Ocular Toxicity Potential: Basic Theory and Techniques -- Robert J. Munger
Emerging Imaging Technologies for Assessing Ocular Toxicity in Laboratory Animals -- T. Michael Nork
Emerging Electrophysiological Technologies for Assessing Ocular Toxicity in Laboratory Animals -- James N. Ver Hoeve
Toxicologic Pathology of the Eye: Histologic Preparation and Alterations of the Anterior Segment -- Kenneth A. Schafer
Toxicologic Pathology of the Eye: Alterations of the Lens and Posterior Segment -- Kenneth A. Schafer
Nonclinical Regulatory Aspects for Ophthalmic Drugs -- Andrea B. Weir
Ocular Toxicity Regulatory Considerations for Nondrug Food and Drug Administration (FDA) Products and the Environmental Protection Agency (EPA) -- Christopher Bartlett.

Edition Notes

Includes bibliographical references and index.

Published in
New York
Series
Molecular and integrative toxicology, Molecular and integrative toxicology

Classifications

Dewey Decimal Class
617.7/1
Library of Congress
RE901.T67 A85 2013, RM1-950RE1-994QL1-99, RM300-666

The Physical Object

Pagination
xiv, 319 pages
Number of pages
319

ID Numbers

Open Library
OL31115661M
ISBN 10
1627031634
ISBN 13
9781627031639, 9781627031646
LCCN
2012951925
OCLC/WorldCat
808417512

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September 12, 2021 Edited by ImportBot import existing book
November 13, 2020 Created by MARC Bot import new book