In the scant few weeks since an explosion decimated New York City, sixteen year old Jess has lived through unimaginable. Only two type of people are left: chasers, infected with a virus that turns them into bloodthirsty killing machines and those they hunt. Jess isn't waiting to be a victim. There's a collective of survivors in the city. Once he's located them, they can find some way out of Manhattan and Jesse can get help for those he's guiltily leaving behind.