Failed surgeon David McBride is in exile from the surgical community after making a costly error in judgment. Down but not out, he perseveres and is given a second chance to establish a career in surgery. But, as David stands on the threshold of a new life, the malignant underside of his fellow man intervenes. Under the threat of violence, David is forced to perform illegal organ harvests in a makeshift operating room hidden in a dilapidated meatpacking warehouse in lower Manhattan. Unable to resolve the excruciating moral dilemma faced each time he invades the body of an unwilling victim, David fights to free himself from the situation and in the process, loses everything. When he finally loses the last shred of his humanity, he seeks revenge with surgical precision ... and instrumentation.