An edition of Decoding the genomic control of immune reactions
(2007)
Decoding the genomic control of immune reactions
by Novartis Foundation
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This book explores existing and potential strategies for using the genome sequences of human, mouse, other vertebrates and human pathogens to solve key problems in the treatment of immunological diseases and chronic infections. The assembled genome sequences now provide important opportunities for solving these problems, but a major bottleneck is the identification of key sequences and circuits controlling the relevant immune reactions. This will require innovative, interdisciplinary and collaborative strategies of a scale and complexity we are only now beginning to comprehend.
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Decoding the Genomic Control of Immune Reactions
2007, Wiley & Sons, Incorporated, John
in English
1282345885 9781282345881
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Book Details
Table of Contents
Transcriptional regulatory networks in macrophages / D.A. Hume ... [et al.]
The RIKEN mouse transcriptome: Lessons learned and implications for the regulation of immune reactions / C. Schonbach
Molecular pathways for lymphangiogenesis and their role in human disease / S.A. Stacker ... [et al.]
Specifying the patterns of immune cell migration / J.G. Cyster
Human monogenic disorders that confer predisposition to specific infections / C. Picard ... [et al.]
The genetic control of susceptibility to mycobacterium tuberculosis / W.J. Britton ... [et al.]
Th2 lymphoproliferative disorders resulting from defective LAT signalosomes / B. Malissen ... [et al.]
Genetic analysis of systemic autoimmunity / C.G. Vinuesa and M.C. Cook
Genetic resistance to smallpox: Lessons from mousepox / G. Karupiah ... [et al.]
The AcB/BcA recombinant congenic strains of mice: Strategies for phenotype dissection, mapping and cloning of quantitative trait genes / A. Fortin ... [et al.]
Genetic control of host-pathogen interactions in mice / G. Min-Oo ... [et al.]
Mycobacterium tuberculosis and its ability to resist immunity / D. Young and A. O'Garra
Systems genetics: The next generation in genetics research? / G. Morahan and R.W. Williams
Regulation of the immune system in metazoan parasite infections / R. Maizels
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Includes bibliographical references and indexes
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