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Explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. Appropriate for pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action.
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Previews available in: English
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Edition | Availability |
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1
Molecular Biology in Medicinal Chemistry
2006, Wiley & Sons, Incorporated, John
in English
3527605185 9783527605187
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2
Molecular Biology in Medicinal Chemistry
2005, Wiley-VCH Verlag GmbH
in English
3527602666 9783527602667
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3
Molecular biology in medicinal chemistry
2003, Wiley-VCH
in English
- 1. Aufl.
3527304312 9783527304318
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Book Details
Table of Contents
Cellular assays in drug discovery
Gene knockout models
Reporter gene assay systems for the investigation of GPCRs
From the human genome to new drugs: The potential of orphan GPCRs
Stereoselective synthesis with the help of recombinant enzymes
Nucleic acid drugs
Recent trends in enantioseparation of chiral drugs
Affinity chromatography
NMR-based drug discovery
13C- and 15N-Isotopic labeling of proteins
Antibody fragments as crystallization enhancers
Pharmacogenetics: the effect of inherited henetic variation on drug disposition and drug response
Pharmacogenomics of bioavailability and elimination
Toxicogenomics: integration of new molecular biological tools in toxicology.
Edition Notes
Includes bibliographical references and index.
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