Physiologically based pharmacokinetic (PBPK) modeling and simulations

principles, methods, and applications in the pharmaceutical industry

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Last edited by ImportBot
December 19, 2023 | History

Physiologically based pharmacokinetic (PBPK) modeling and simulations

principles, methods, and applications in the pharmaceutical industry

  • 0 Ratings
  • 1 Want to read
  • 0 Currently reading
  • 0 Have read

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Publish Date
Publisher
Wiley
Language
English
Pages
450

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Edition Availability
Cover of: Physiologically-Based Pharmacokinetic (Pbpk) Modeling and Simulations
Physiologically-Based Pharmacokinetic (Pbpk) Modeling and Simulations
2012, Wiley & Sons, Incorporated, John
in English
Cover of: Physiologically based pharmacokinetic (PBPK) modeling and simulations

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Book Details


Table of Contents

Modelling in the pharmaceutical industry
Physiologically-based modelling
A review of pharmacokinetic principles
Physiological model for absorption
Physiological model for distribution
Physiological models for drug metabolism and excretion
Generic whole-body physiologically-based pharmacokinetic modelling
Variability, uncertainty and sensitivity analysis
Evaluation of drug-drug interaction risk with pbpk models
PBPK of biotherapeutics
Data integration and sensitivity analysis
Hypothesis generation and pharmacokinetic predictions
Integration of PBPK and pharmacodynamics
PBPK modelling of populations
PBPK models along the drug discovery and development value chain.

Edition Notes

Includes bibliographical references and index.

Published in
Hoboken, N.J

Classifications

Dewey Decimal Class
615/.7
Library of Congress
RM301.5 .P48 2011, RM301.5.P48 2012

The Physical Object

Pagination
p. ;
Number of pages
450

ID Numbers

Open Library
OL24896067M
ISBN 13
9780470484067
LCCN
2011019939

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History

Download catalog record: RDF / JSON
December 19, 2023 Edited by ImportBot import existing book
September 17, 2021 Edited by ImportBot import existing book
July 29, 2011 Created by LC Bot import new book