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Subjects
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Genetic engineering: manipulating the mechanisms of life
2009, Facts On File
in English
0816066817 9780816066810
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Book Details
Table of Contents
From breeding to a science of heredity
The origins of domestic plants and animals
The rise of agriculture and domestication
Early ideas of inheritance
The girl who gave birth to rabbits
Heredity and the theory of evolution
Gregor mendel discovers the laws of heredity
Classical genetics (1900-1950)
Cell theory and the discovery of chromosomes
The rediscovery of mendel's work
The debate over natural selection
Chromosomes and heredity
Sex and the X-Y chromosomes
Fruit flies and the birth of the modern laboratory
Gene maps
Chromosome puzzles
Maize and "jumping genes"
"One gene makes one enzyme"
Molecular genetics: what genes are and how they work (1950-1970)
Physics stimulates new ways of thinking about genes
Genes are made of DNA
The double helix
RNA is the messenger
The architecture of genes
On-off switches for genes
The flow of information from gene to protein in complex organisms
The rise of genetic engineering (1970-1990)
Recombinant DNA
"Natural" genetic engineering
Molecular cloning and using bacteria as drug factories
DNA sequencing
The polymerase chain reaction (PCR)
Making and marketing genetically modified plants and animals for food
Knock outs, knock ins, and other methods to study gene functions
Beatrice Mintz: a pioneer of mouse genetics
Transgenic animals and models of human disease
DNA fingerprinting
Genetic engineering in the age of genomes
The complexity of genomes
Introns and alternative splicing
Non-coding RNAs
Quality control: how cells detect defective genes
RNA knock outs
Molecular machines
Conditional mutagenesis
Other methods of controlling the output of genes
Molecular medicine and gene therapies
Personalized medicine in the genome age
DNA vaccines and t cell therapies
Ethics and genetic engineering
Reproductive cloning
Therapeutic cloning and experiments with human cells
Genetic testing and concerns about eugenics
GM foods and the rise of environmental movements
Owning genes, genomes, and living beings
A look farther ahead.
Edition Notes
Includes bibliographical references and index.