An edition of Beyond thalidomide (2007)

Beyond thalidomide

birth defects explained

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Beyond thalidomide
Janet McCredie
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Last edited by MARC Bot
May 28, 2023 | History
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An edition of Beyond thalidomide (2007)

Beyond thalidomide

birth defects explained

by

  • 0 Ratings
  • 0 Want to read
  • 0 Currently reading
  • 0 Have read

How do birth defects happen? Why does thalidomide mutilate the embryo? In this challenging text the author takes a new approach to the resulting disordered anatomy and demonstrates that the skeletal defects seen are inconsistent with primary bone disease, but indicate primary damage to the embryonic sensory nerves--neural crest injury. This book will be of interest to those involved with birth defects.

Publish Date
Publisher
Royal Society of Medicine Press
Language
English
Pages
418

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Subjects
Abnormalities, Drug-Induced, Congenital Limb Deformities, Chemically induced, Thalidomide, Adverse effects, Human Abnormalities, Side effects

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Edition Availability
Cover of: Beyond thalidomide
Beyond thalidomide: birth defects explained
2007, Royal Society of Medicine Press
in English
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Book Details

Table of Contents

The thalidomide epidemic
Pharmacology of thalidomide: interaction with the human embryo
Animal studies
Thalidomide polyneuropathy
Clinical radiology
Terminology, classification and the rejection of authority
The pattern of the disease: first radiological analysis (Sydney)
Verification of the disease pattern: second radiological analysis (London)
Congenital reductions of the radius
Congenital dislocation
Congenital synostosis
The hypothesis of neural crest injury
The neural crest
Neurotrophism
Nerve in limb bud
Regeneration and embryogenesis
Neural crest ablation and limb morphogenesis
Thalidomide deformities and their nerve supply: first morphometirc study in rabbits
Thalidomide deformities and their nerve supply: second morphometric study in rabbits
The sensory nerve supply of bone
The sclerotomes
Sclerotome aplasia/subtraction
Sclerotome aplasia/subtraction in 203 cases
Radial/tibial dysmelia: limb reductions typical of thalidomide
Associated internal malformations and their embryology
Neurotomes and multiple malformation syndromes
Hands and feet in thalidomide embryopathy: histology and sclerotomes in the digits
Other disorders of similar sclerotomes
Segmental and truncal neuorpathies in sclerotomes not affected by thalidomide
Review of actions of thalidomide
Conclusion: beyond thalidomide.

Edition Notes

Includes bibliographical references and index.

Published in
London, Ashland, OH

Classifications

Dewey Decimal Class
616.043
Library of Congress
RG626 .M33 2007

The Physical Object

Pagination
xii, 418 p.
Number of pages
418

ID Numbers

Open Library
OL48033549M
ISBN 10
1853157414
ISBN 13
9781853157417
OCLC/WorldCat
182662820

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May 28, 2023 Created by MARC Bot Imported from harvard_bibliographic_metadata record