Solid-Phase Extraction (SPE) offers accessible, up-to-date coverage of every aspect of this useful separation tool, from how it works and where it works to recent advances in equipment and techniques.

Divided into three main parts, the book begins with a clear explanation of basic SPE concepts - including theory, chemistry, and mechanisms of interaction as well as methods development, troubleshooting, and optimization. The next section presents an in-depth look at SPE applications, with separate chapters devoted to clinical, environmental, and natural product chemistry.

Numerous examples drawn from each of these three areas illustrate SPE in action in the real world, successfully bridging the gap between principles and practice.

The final section of the book discusses the latest SPE technology, with detailed coverage of the automation process, solid-phase extraction disks, and innovations such as solid-phase microextraction and small-volume solid-phase extraction. Suggested reading and references are included throughout, providing a useful spring-board for further research and study.