2017: When Angela Creighton discovers a mysterious letter containing a life-shattering confession, she is determined to find the intended recipient. Her search takes her back to the 1970s when a group of daring women operated an illegal underground abortion network in Toronto known only by its whispered code name: Jane.

1971: As a teenager, Dr. Evelyn Taylor was sent to a home for “fallen” women where she was forced to give up her baby for adoption—a trauma she has never recovered from. Despite the constant threat of arrest, she joins the Jane Network as an abortion provider, determined to give other women the choice she never had.

1980: After discovering a shocking secret about her family, twenty-year-old Nancy Mitchell begins to question everything she has ever known. When she unexpectedly becomes pregnant, she feels like she has no one to turn to for help. Grappling with her decision, she locates “Jane” and finds a place of her own alongside Dr. Taylor within the network’s ranks, but she can never escape the lies that haunt her.