Check nearby libraries
Buy this book
![Loading indicator](/images/ajax-loader-bar.gif)
Nitrogen-centered aziridinyl radicals exhibit different properties from other types of nitrogen-centered radicals and have great potential for the construction of nitrogen-containing heterocycles. The studies of nitrogen-centered aziridinyl radicals in the literature have been limited to basic physical and chemical properties, and their synthetic utility remains undeveloped. We have found that nitrogen-centered azindinyl radicals can be generated through homolysis of N-haloaziridines which can be easily produced upon treatment of N-bromosuccinimide or N-iodosuccinimide with aziridinys. This methodology has been applied to the synthesis of a variety of beta-haloaziridines in moderate to good yields. Further transformation into piperazine derivatives was achieved via nucleophilic substitution at the beta position and oxalyl chloride coupling reaction. The resulting structure is present in a potential selective brain serotonin (5HT2A) antagonist.
Check nearby libraries
Buy this book
![Loading indicator](/images/ajax-loader-bar.gif)
Showing 1 featured edition. View all 1 editions?
Edition | Availability |
---|---|
1
Nitrogen-centered aziridinyl radicals and their synthetic applications.
2007
in English
0494272767 9780494272763
|
aaaa
Libraries near you:
WorldCat
|
Book Details
Edition Notes
Source: Masters Abstracts International, Volume: 45-06, page: 3162.
Thesis (M.Sc.)--University of Toronto, 2007.
Electronic version licensed for access by U. of T. users.
ROBARTS MICROTEXT copy on microfiche.
The Physical Object
ID Numbers
Community Reviews (0)
Feedback?History
- Created November 1, 2008
- 2 revisions
Wikipedia citation
×CloseCopy and paste this code into your Wikipedia page. Need help?
December 15, 2009 | Edited by WorkBot | link works |
November 1, 2008 | Created by ImportBot | Imported from University of Toronto MARC record |