The collection of texts that make up this work, whose opening theme is Regional Development and its Science, is a modest contribution to regional studies. In particular, the texts have an economic emphasis, given the author's experience, and deal with topics ranging from regional development as the subject of a "Science of Regional Development" to issues related to the dynamics of regions, particularly regional economies. Consequently, taken as a whole, the texts present reflections on economic polarization, structural changes in regional economies, specializations, spatial forces, especially territorial ones, among others. Certainly, the texts presented here do not exhaust the debate on the "Science of Regional Development" or on the mechanisms and elements of regional development. They are a contribution from an economic perspective, with the aim of stimulating theoretical and empirical discussions about the development process in the regions.