MARC Record from marc_uic

LEADER: 05395cam a2200757 i 4500
001 9933893012005897
005 20200409161954.0
008 811009s1981 nyua b 101 0 eng
010 $a81017839
015 $aGB8214704$2bnb
016 7 $a8208907$2DNLM
019 $a8573627$a16540411
020 $a0306408902$q(hbk)
020 $a9780306408908$q(hbk)
035 $a763455-01carli_network
035 $a(OCoLC)ocm07925767$z(OCoLC)8573627$z(OCoLC)16540411
035 $a(EIUdb)74257
035 $a(EXLNZ-01CARLI_NETWORK)991038018659705816
040 $aDLC$beng$erda$cDLC$dUKM$dNLM$dOCL$dMUQ$dEIA$dBAKER$dBTCTA$dMCS$dBDX$dYDXCP$dOCLCO$dOCLCF$dOCLCQ$dOCLCO$dOCL$dOCLCO$dOCLCQ$dOCLCO$dTXI$dOCLCO$dEIUdb
049 $aIADA
050 4 $aRA566$b.S95 1980
050 4 $aTD172$b.E5 vol. 22
060 00 $aW1$bEN986F v.22 1981
060 10 $aWA 671$bS9895 1980s
082 00 $a615.9/07$219
088 $aEPA-600/9-82-004
111 2 $aSymposium on the Application of Short-Term Bioassays in the Fractionation and Analysis of Complex Environmental Mixtures$n(2nd :$d1980 :$cWilliamsburg, Va.)
245 10 $aShort-term bioassays in the analysis of complex environmental mixtures II /$cedited by Michael D. Waters, Shahbeg S. Sandhu, Joellen Lewtas Huisingh, Larry Claxton and Stephen Nesnow.
264 1 $aNew York :$bPlenum Press,$c[1981]
300 $axv, 524 pages :$billustrations ;$c26 cm.
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
338 $avolume$bnc$2rdacarrier
490 1 $aEnvironmental science research ;$vv. 22
504 $aIncludes bibliographical references and index.
500 $a"Proceedings of the Second Symposium on the Application of Short-Term Bioassays in the Fractionation and Analysis of Complex Environmental Mixtures, held in Williamsburg, Virginia, March 4-7, 1980"--Title page verso.
505 2 $aAmbient air -- Drinking water and aqueous effluents -- Terrestrial systems -- Mobile sources -- Stationary source -- Hazard assessment.
520 $aMore than one hundred short-term bioassays are now available for detecting the toxicity, mutagenicity, and potential carcinogenicity of chemicals. These bioassays were developed and validated with individual compounds, and their principal application was perceived to be in evaluating the health hazard of such materials. However, man is rarely exposed to single chemicals; his exposure to hazardous chemicals is more commonly a multifactorial phenomenon. Although chemical analysis can be used to detect known hazardous compounds, it would be a staggering and expensive task to analyze large numbers of samples for all known or suspected hazardous constituents. Furthermore, the biological activity of a complex mixture cannot be reliably predicted from knowledge of its components. On the other hand, bioassays alone cannot tell us which components of complex mixtures are responsible for the biological activity detected. Thus, cost effectiveness and technical feasibility dictate stepwise and perhaps iterative application -of both chemical and biological methods in evaluating the health effects of complex environmental mixtures. Through the coupling of reliable biological detection systems with methods of chemical fractionation and analysis, it is frequently possible to isolate the individual chemical species that show biological activity. Initially, complex mixtures may be separated and bioassayed in carefully defined chemical fractions. The results of such short-term screening bioassays then may be used td guide the course of further fractionation and to determine the need for more stringent and comprehensive biological testing -- Provided by the publisher.
650 0 $aEnvironmental toxicology$vCongresses.
650 0 $aToxicity testing$vCongresses.
650 0 $aBiological assay$vCongresses.
650 0 $aEnvironmental chemistry$vCongresses.
650 2 $aBiological Assay.
650 2 $aCarcinogens, Environmental$xanalysis.
650 2 $aEnvironmental Pollutants$xanalysis.
650 6 $aÉcotoxicologie$vCongrès.
650 6 $aMutagénicité$xCongrès.
650 6 $aEssais biologiques$xCongrès.
650 6 $aChimie de l'environnement$vCongrès.
650 7 $aBiological assay.$2fast$0(OCoLC)fst00832194
650 7 $aEnvironmental chemistry.$2fast$0(OCoLC)fst00912860
650 7 $aEnvironmental toxicology.$2fast$0(OCoLC)fst00913536
650 7 $aToxicity testing.$2fast$0(OCoLC)fst01153336
653 $aEnvironment$aPollutants: Chemicals$aShort term biological assay - Conference proceedings
655 2 $aCongresses.
655 7 $aConference papers and proceedings.$2fast$0(OCoLC)fst01423772
700 1 $aWaters, Michael D.,$eeditor.
700 1 $aSandhu, Shahbeg S.,$eeditor.
700 1 $aHuisingh, Joellen Lewtas,$eeditor.
700 1 $aClaxton, Larry D.,$eeditor.
700 1 $aNesnow, Stephen,$d1941-$eeditor.
776 08 $iOnline version:$aSymposium on the Application of Short-Term Bioassays in the Fractionation and Analysis of Complex Environmental Mixtures (2nd : 1980 : Williamsburg, Va.).$tShort-term bioassays in the analysis of complex environmental mixtures II.$dNew York : Plenum Press, [1981]$w(OCoLC)610465546
830 0 $aEnvironmental science research ;$vv. 22.
959 $a(EIUdb)74257
959 $a(UICdb)338930$9LOCAL
994 $a92$bIAD