MARC Record from Library of Congress

LEADER: 05653cam a2200493 i 4500
001 2014432643
003 DLC
005 20141017085903.0
008 140703t20002000enka b 101 0 eng c
010 $a 2014432643
015 $aGBA0V9581$2bnb
016 7 $a009099040$2Uk
020 $a0854048308
020 $a9780854048304
035 $a(OCoLC)ocm45263524
040 $aESU$beng$cESU$erda$dUKM$dIXA$dAGL$dOCLCQ$dBAKER$dUBA$dYDXCP$dOKU$dOCLCQ$dAGL$dOSU$dGEBAY$dBDX$dS4S$dOCLCF$dOCLCA$dWAU$dUKMGB$dOCLCO$dDLC
042 $apcc
072 0 $aX300
084 $aHE 41$2blsrissc
084 $aLW 78$2blsrissc
050 00 $aQD415$b.I54 1999
082 00 $a615.3/2$223
111 2 $aInternational Meeting Biodiversity: A Source of New Leads for the Pharmaceutical and Agrochemical Industries$d(1999 :$cUniversity of St. Andrews)
245 10 $aBiodiversity :$bnew leads for the pharmaceutical and agrochemical industries /$cedited by Stephen K. Wrigley ... [et al.].
264 1 $aCambridge, UK :$bRoyal Society of Chemistry,$c[2000]
264 4 $c©2000
300 $a313 pages :$billustrations ;$c24 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
338 $avolume$bnc$2rdacarrier
490 1 $aSpecial publication ;$vno. 257
500 $a"The proceedings of the International Meeting Biodiversity: A Source of New Leads for the Pharmaceutical and Agrochemical Industries held on 5-8 September 1999 at the University of St Andrews"--Title page verso.
500 $aConference organized by the Biotechnology Group of the Industrial Division of The Royal Society of Chemistry.
520 8 $a"The continuing quest for new drugs and agrochemicals has seen researchers looking to the natural world for potential products. Plants and microorganisms have long been investigated as sources of new lead compounds, but the scope of this book has been widened to include substances derived from marine organisms. Advances in genetic engineering, high throughput screening and structure elucidation have also opened up further avenues for exploration. Competitive pressure from the field of combinatorial chemistry has expedited new approaches to natural product analysis and stimulated debate on the industrial utilization of natural products. Biodiversity: New Leads for the Pharmaceutical and Agrochemical Industries reviews and discusses aspects of modern natural products research. The central theme of many articles is the sustainable use of global biodiversity. Microbial, plant and marine products are presented as the sources of new drugs, including antifungal products, antibiotics, anticancer agents and animal health products. There is also coverage of the biosynthesis of polyketides and the chemical synthesis of natural products and their derivatives"--Page 4 of cover.
504 $aIncludes bibliographical references and index.
505 0 $aMicrobial natural products : a past with a future / A.L. Demain -- New concepts and approaches to biodiversity / D.F. Marshall and J.R. Hillman -- Natural products drug discovery at the National Cancer Institute : past achievements and new directions for the new millennium / G.M. Cragg, M.R. Boyd, Y.F. Hallock, D.J. Newman, E.A. Sausville and M.K. Wolpert -- Secondary metabolites as a vital source of animal health products / J.C. Ruddock -- The relationship between natural products and synthetic chemistry in the discovery process / S. Brewer -- Natural products vs. combinatorials : a case study / D. Baker, U. Mocek and C. Garr -- Mushrooms, microbes and medicines / A. Buss and M.A. Hayes -- Signal transduction inhibitors from microorganisms / S.K. Wrigley, D.A. Kau, B. Waters and J.E. Davies -- Novel inhibitors of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579 / J. Thirkettle -- Marine organisms as a source of novel lead structures for drug development / A.E. Wright -- The anticancer dolastatins as cyanobacterial metabolites / G.G. Harrigan, H. Luesch, R.E. Moore and V.J. Paul -- A Cu²⁺ selective marine metabolite / L.A. Morris and M. Jaspars -- Water soluble bioactive alkaloids / A.A. Watson and R.J. Nash -- 'Lessons from nature' : can ecology provide new leads in the search for novel bioactive chemicals from tropical rainforests? / P. Reddell and V. Gordon -- Brazilian biodiversity : a source of phytomedicines, natural drugs and leads for the pharmaceutical and agrochemical industries / B. Gilbert -- A modern perspective to the traditional use of plants in the Highlands of Scotland / R. Constadouros -- In vivo and in vitro biosynthetic studies : understanding and exploiting natural pathways / T.J. Simpson -- Fused ring aromatic polyketides are formed by different cyclisation pathways in fungi and streptomycetes / R. Thomas -- The strobilurin fungicides--from mushroom to molecule to market / J.M. Clough -- A synthesis of (+)-Prelog-Djerassi lactonic acid / S.D. Hiscock, P.B. Hitchcock and P.J. Parsons -- N-([alpha]-aminoacyl)-5ʹ-O-sulfamoyladenosines : natural product based inhibitors of amino acyl tRNA synthetases / K. Beautemont, E.J.T. Chrystal, J. Howard and S.M. Ridley.
650 0 $aNatural products$vCongresses.
650 0 $aBiosynthesis$vCongresses.
650 0 $aDrug development$vCongresses.
650 0 $aAgricultural chemicals$vCongresses.
700 1 $aWrigley, Stephen,$eeditor.
710 2 $aRoyal Society of Chemistry (Great Britain).$bBiotechnology Group,$eorganizer.
710 2 $aRoyal Society of Chemistry (Great Britain),$eissuing body,$epublisher.
830 0 $aSpecial publication (Royal Society of Chemistry (Great Britain)) ;$vno. 257.