| Record ID | marc_loc_2016/BooksAll.2016.part41.utf8:131397739:3789 |
| Source | Library of Congress |
| Download Link | /show-records/marc_loc_2016/BooksAll.2016.part41.utf8:131397739:3789?format=raw |
LEADER: 03789cam a2200541 i 4500
001 2013951224
003 DLC
005 20140911081857.0
008 130924t20142014nyua b 001 0 eng
010 $a 2013951224
016 7 $a101626755$2DNLM
020 $a9781627037297 (alk. paper)
020 $a1627037292 (alk. paper)
020 $z978627037303 (eBook)
035 $a(OCoLC)ocn857961536
040 $aNLM$beng$cNLM$erda$dBTCTA$dYDXCP$dIDL$dCDX$dOCLCO$dCHVBK$dDEBBG$dOCLCO$dOCLCF$dSCB$dDLC
042 $anlmcopyc$alccopycat
050 00 $aQP623.5.C36$bT48 2014
060 00 $aW1$bME9616J v.1103 2014
060 10 $aQU 25
082 04 $a572.8/8$223
245 00 $aTherapeutic applications of ribozymes and riboswitches :$bmethods and protocols /$cedited by Daniel Lafontaine and Audrey Dubé, Department of Biology, Université de Sherbrooke, Sherbrooke, QC, Canada.
264 1 $aNew York :$bHumana Press,$c[2014]
264 4 $c©2014
300 $axi, 278 pages :$billustrations (some color) ;$c26 cm.
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
338 $avolume$bnc$2rdacarrier
490 1 $aMethods in molecular biology,$x1064-3745 ;$v1103
490 1 $aSpringer protocols
504 $aIncludes bibliographical references and index.
505 00 $tIdentification of regulatory RNA in bacterial genomes by genome-scale mapping of transcription start sites --$tScreening inhibitory potential of anti-HIV RT RNA aptamers --$tDesign and evaluation of clinically relevant SOFA-HDV ribozymes targeting HIV RNA --$tDirecting RNase P-mediated cleavage of target mRNAs by engineered external guide sequences in cultured cells --$tDesign and analysis of hammerhead ribozyme activity against an artificial gene target --$tKnockdown strategies for the study of proprotein convertases and proliferation in prostate cancer cells --$tUse of tumor-targeting trans-splicing ribozyme for cancer treatment --$tCharacterization of hairpin ribozyme reactions --$tFinding instances of riboswitches and ribozymes by homology search of structured RNA with infernal --$tStructure-based virtual screening for the identification of RNA- binding ligands --$tProbing riboswitch binding sites with molecular docking, focused libraries, and in-line probing assays --$tDiscovery of small molecule modifiers of micrornas for the treatment of HCV infection --$tBacterial flavin mononucleotide riboswitches as targets for flavin analogs --$tConstruction and application of riboswitch-based sensors that detect metabolites within bacterial cells --$tScreening assays to identify artificial glmS ribozyme activators --$tAnalysis of riboswitch structure and ligand binding using small-angle X-ray scattering (SAXS) --$tUse of SHAPE to select 2AP substitution sites for RNA-ligand interactions and dynamics studies --$tCell internalization SELEX: In vitro selection for molecules that internalize into cells --$tDNA electronic switches based on analyte-responsive aptamers.
650 0 $aCatalytic RNA$vLaboratory manuals.
650 0 $aRiboswitches$vLaboratory manuals.
650 12 $aRNA, Catalytic$xtherapeutic use$vLaboratory Manuals.
650 22 $aRiboswitch$vLaboratory Manuals.
655 2 $aLaboratory Manuals.
650 7 $aCatalytic RNA.$2fast
650 7 $aRiboswitches.$2fast
655 7 $aHandbooks, manuals, etc.$2fast
650 07 $aRiboswitch.$2gnd
650 07 $aRibozym.$2gnd
650 07 $aTherapie.$2gnd
700 1 $aLafontaine, Daniel,$eeditor.
700 1 $aDubé, Audrey$c(Biologist),$eeditor.
830 0 $aMethods in molecular biology (Clifton, N.J.) ;$vv. 1103.$x1064-3745
830 0 $aSpringer protocols (Series)$x1949-2448
856 41 $3Table of contents$uhttp://catdir.loc.gov/catdir/enhancements/fy1404/2013951224-t.html