MARC Record from marc_columbia

LEADER: 04914cam a2200673 i 4500
001 13199552
005 20180328111902.0
008 160211t20162016enkaf b 001 0 eng
010 $a 2016933212
035 $a(OCoLC)ocn938360569
040 $aNLM$beng$erda$cNLM$dYDXCP$dDLC$dEUW$dYDX$dOCLCF$dFM0$dCOO$dVP@$dLTSCA$dOBE$dZQP$dMNU$dRIU$dYOU$dNDD$dOCLCO$dOCLCA$dOCLCQ$dOCLCO$dDEBBG$dOCLCO$dERASA$dBDX$dBTCTA$dNLE$dCHVBK$dOCLCQ$dUPM$dOCLCA
016 7 $a101697385$2DNLM
019 $a944160208$a980911806
020 $a9780198766827$q(hardback)
020 $a0198766823$q(hardback)
029 0 $aNLM$b101697385
029 1 $aAU@$b000058565381
029 1 $aCHBIS$b010696594
029 1 $aCHDSB$b006507294
029 1 $aCHVBK$b362550832
029 1 $aCHVBK$b36670799X
029 1 $aDEBBG$bBV044192661
029 1 $aGBVCP$b870023268
029 1 $aUNITY$b138481679
035 $a(OCoLC)938360569$z(OCoLC)944160208$z(OCoLC)980911806
042 $alccopycat$apcc
050 00 $aQH442$b.P375 2016
060 00 $a2016 I-949
060 10 $aQU 550.5.G47
082 04 $a660.6/5$223
084 $aWG 1600$2rvk
049 $aZCUA
100 1 $aParrington, John,$eauthor.
245 10 $aRedesigning life :$bhow genome editing will transform the world /$cJohn Parrington.
264 1 $aOxford, United Kingdom :$bOxford University Press,$c[2016]
264 4 $c©2016
300 $axii, 352 pages, 2 unnumbered pages of plates :$billustrations (some color) ;$c24 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
338 $avolume$bnc$2rdacarrier
504 $aIncludes bibliographical references (pages 293-336) and indexes.
505 0 $aIntroduction : the gene revolution -- Natural born mutants -- Supersize my mouse -- Light as a life tool -- The gene scissors -- Next year's models -- The molecular farm -- New gene therapy -- Regenerating life -- Life as a machine -- A redesigned planet?
520 $aSince the birth of civilisation, human beings have manipulated other life-forms. We have selectively bred plants and animals for thousands of years to maximize agricultural production and cater to our tastes in pets. The observation of the creation of artificial animal and plant variants was a key stimulant for Charles Darwin's theory of evolution. The ability to directly engineer the genomes of organisms first became possible in the 1970s, when the gene for human insulin was introduced into bacteria to produce this protein for diabetics. At the same time, mice were modified to produce human growth hormone, and grew huge as a result. But these were only our first tottering steps into the possibilities of genetic engineering. In the past few years, the pace of progress has accelerated enormously. We can now cut and paste genes using molecular scissors with astonishing ease, and the new technology of genome editing can be applied to practically any species of plants or animals. 'Mutation chain reaction' can be used to alter the genes of a population of pests, such as flies; as the modified creatures breed, the mutation is spread through the population, so that within a few generations the organism is almost completely altered. At the same time, scientists are also beginning to synthesize new organisms from scratch. These new technologies hold much promise for improving lives. Genome editing has already been used clinically to treat AIDS patients, by genetically modifying their white blood cells to be resistant to HIV. In agriculture, genome editing could be used to engineer species with increased food output, and the ability to thrive in challenging climates. New bacterial forms may be used to generate energy. John Parrington explains the nature and possibilities of these new scientific developments, which could usher in a brave, new world. We must rapidly come to understand its implications if we are to direct its huge potential to the good of humanity and the planet.
650 0 $aGenomics.
650 0 $aGenetic engineering.
650 12 $aGene Editing$xtrends.$0(DNLM)D000072669Q000639
650 22 $aGenetic Engineering$xtrends.$0(DNLM)D005818Q000639
650 22 $aGenomics$xtrends.$0(DNLM)D023281Q000639
650 7 $aGenetic engineering.$2fast$0(OCoLC)fst00940027
650 7 $aGenomics.$2fast$0(OCoLC)fst00940228
650 7 $aTechnikbewertung$2gnd$0(DE-588)4078176-8
650 7 $aGenome Editing$2gnd$0(DE-588)1116095971
650 7 $aBioethik$2gnd$0(DE-588)4006791-9
650 4 $aGenomics$xtrends.
650 4 $aGenetic Engineering$xtrends.
856 41 $3Table of contents$uhttps://www.loc.gov/catdir/enhancements/fy1621/2016933212-t.html
856 42 $3Contributor biographical information$uhttps://www.loc.gov/catdir/enhancements/fy1621/2016933212-b.html
856 42 $3Publisher description$uhttps://www.loc.gov/catdir/enhancements/fy1621/2016933212-d.html
852 00 $bbar$hQH442$i.P375 2016