MARC Record from marc_columbia

LEADER: 03295cam a2200397Ii 4500
001 12678860
005 20170918170644.0
008 170502t20172017dcua b 000 0 eng d
020 $a9780309453295$qpaperback
020 $a0309453291$qpaperback
024 7 $a10.17226/24632$2doi
035 $a(OCoLC)ocn985121178
035 $a(OCoLC)985121178
035 $a(NNC)12678860
040 $aTKN$beng$erda$cTKN$dOCLCO$dSOI$dOCLCO$dNRC$dOCLCO$dKSU$dCOO$dOCLCO
050 4 $aRB155.65$b.N38 2017
110 2 $aNational Academies of Sciences, Engineering, and Medicine (U.S.).$bCommittee on the Evidence Base for Genetic Testing,$eauthor.
245 13 $aAn evidence framework for genetic testing /$cCommittee on the Evidence Base for Genetic Testing, Board on the Health of Select Populations, Board on Health Care Services, Health and Medicine Division, a report of the National Academies of Sciences, Engineering, Medicine.
264 1 $aWashington, DC :$bthe National Academies Press,$c[2017]
264 4 $c©2017.
300 $axii, 136 pages :$billustrations ;$c28 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
338 $avolume$bnc$2rdacarrier
520 $a"Advances in genetics and genomics are transforming medical practice, resulting in a dramatic growth of genetic testing in the health care system. The rapid development of new technologies, however, has also brought challenges, including the need for rigorous evaluation of the validity and utility of genetic tests, questions regarding the best ways to incorporate them into medical practice, and how to weigh their cost against potential short- and long-term benefits. As the availability of genetic tests increases so do concerns about the achievement of meaningful improvements in clinical outcomes, costs of testing, and the potential for accentuating medical care inequality. Given the rapid pace in the development of genetic tests and new testing technologies, An Evidence framework for genetic testing seeks to advance the development of an adequate evidence base for genetic tests to improve patient care and treatment. Additionally, this report recommends a framework for decision-making regarding the use of genetic tests in clinical care"--Publisher's description.
504 $aIncludes bibliographical references (pages 111-130).
505 0 $aGenetic testing -- Genetic test assessment -- Evidence -- An evidence framework for genetic testing -- Appendix A. Understanding genetic variance and phenotype expression -- Appendix B: the GETT checklist -- Appendix C:. Using evidence to inform clinical and policy decision.
650 0 $aGenetic screening.
650 0 $aGene expression$xTesting.
650 0 $aMedical genetics.
650 0 $aHuman chromosome abnormalities$xDiagnosis.
650 12 $aGenetic Testing$xstandards.$0(DNLM)D005820Q000592
650 22 $aGenomics$xstandards.$0(DNLM)D023281Q000592
650 22 $aEvidence-Based Medicine.$0(DNLM)D019317
776 08 $iOnline version:$aNational Academies of Sciences, Engineering, and Medicine (U.S.). Committee on the Evidence Base for Genetic Testing.$tEvidence framework for genetic testing$dWashington, D.C. :$bNational Academies Press, [2017]$z9780309453295$w(OCoLC)979995662
852 00 $boff,sci$hRB155.65$i.N38 2017g