MARC Record from marc_columbia

LEADER: 04432cam a2200385Ii 4500
001 11541652
005 20160123212515.0
008 150401s2015 dcuad b 000 0 eng d
020 $a0309316529
020 $a9780309316521
035 $a(OCoLC)ocn913921593
035 $a(OCoLC)913921593
035 $a(NNC)11541652
040 $aYDXCP$beng$erda$cYDXCP$dOCLCO$dNRZ$dIXA
090 $aHD9999
090 $aHD9999.B443$bU6445 2015
245 00 $aIndustrialization of biology :$ba roadmap to accelerate the advanced manufacturing of chemicals /$cCommittee on Industrialization of Biology: A Roadmap to Accelerate the Advanced Manufacturing of Chemicals, Board on Chemical Sciences and Technology, Board on Life Sciences, Division on Earth and Life Studies, National Research Council of the National Academies.
264 1 $aWashington, D.C. :$bNational Academies Press,$c2015.
264 4 $c©2015
300 $axvi, 150 pages :$bcolor illustrations, color charts ;$c23 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
338 $avolume$bnc$2rdacarrier
505 0 $aIndustrial Biotechnology: Past and Present -- Vision of the Future: What New Chemicals Could Be Made? -- How Do We Get There? -- What Is Success and How to Get There: Recommendations -- References -- Appendix A: Glossary -- Appendix B: The Current Regulatory Framework -- Appendix C: Committee Member and Staff Biographies -- Appendix D: Workshop Agenda and Attendees -- FIgures S-1 and 5-1 (foldout)
520 $a"The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed."--Publisher's description.
650 0 $aBiotechnology industries.
650 0 $aChemical industry$xTechnological innovations.
650 0 $aChemical industry$zUnited States.
650 0 $aBiotechnology industries$zUnited States.
710 2 $aNational Research Council (U.S.).$bCommittee on Industrialization of Biology : a Roadmap to Accelerate the Advanced Manufacturing of Chemicals,$eauthor.
710 2 $aNational Research Council (U.S.).$bBoard on Chemical Sciences and Technology,$eissuing body.
710 2 $aNational Research Council (U.S.).$bDivision on Earth and Life Studies,$eissuing body.
776 08 $tIndustrialization of biology.$dWashington, D.C. : The National Academies Press, [2015]$z9780309316538$w(DLC) 2015937241$w(OCoLC)906010242
856 41 $3National Academies Press$uhttp://www.nap.edu/openbook.php?record_id=19001
852 00 $boff,sci$hHD9999.B443$iU6445 2015g