MARC Record from marc_columbia

LEADER: 04979cam a2200613 i 4500
001 10933483
005 20190121131207.0
007 cr cn|
008 140828s2014 dcua b 100 0 eng
010 $a 2014501915
016 7 $a101646673$2DNLM
020 $a9780309304948
020 $a0309304946
035 $a(OCoLC)900260602
035 $a(OCoLC)ocn900260602
035 $a(NNC)10933483
040 $aNLM$beng$erda$cNLM$dOCLCO$dUNL$dDLC$dOCLCO$dOCL$dOCLCO
042 $anlmcopyc
050 00 $aRB155$b.A763 2014
060 00 $a2014 M-662
060 10 $aQZ 52
082 04 $a616/.042$223
100 1 $aBeachy, Sarah H.,$erapporteur.
245 10 $aAssessing Genomic Sequencing Information for Health Care Decision Making :$bworkshop summary /$cRoundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy ; Sarah H. Beachy, Samuel G. Johnson, Steve Olson, and Adam C. Berger, rapporteurs ; Institute of Medicine of the National Academies.
264 1 $aWashington, D.C. :$bNational Academies Press,$c[2014]
264 4 $c©2014.
300 $axx, 105 pages :$billustrations ;$c23 cm
336 $atext$2rdacontent
337 $aunmediated$2rdamedia
338 $avolume$2rdacarrier
504 $aIncludes bibliographical references.
505 0 $aIntroduction -- How evidence is gathered and evaluated -- Patient care and health decisions -- The development of practice guidelines -- How insurers decide whether to pay for testing -- Addressing challenges.
520 $a"Rapid advances in technology have lowered the cost of sequencing an individual's genome from the several billion dollars that it cost a decade ago to just a few thousand dollars today and have correspondingly greatly expanded the use of genomic information in medicine. Because of the lack of evidence available for assessing variants, evaluation bodies have made only a few recommendations for the use of genetic tests in health care. For example, organizations, such as the Evaluation of Genomic Applications in Practice and Prevention working group, have sought to set standards for the kinds of evaluations needed to make population-level health decisions. However, due to insufficient evidence, it has been challenging to recommend the use of a genetic test. An additional challenge to using large-scale sequencing in the clinic is that it may uncover "secondary," or "incidental," findings - genetic variants that have been associated with a disease but that are not necessarily related to the conditions that led to the decision to use genomic testing. Furthermore, as more genetic variants are associated with diseases, new information becomes available about genomic tests performed previously, which raises issues about how and whether to return this information to physicians and patients and also about who is responsible for the information. To help develop a better understanding of how genomic information is used for healthcare decision making, the Roundtable on Translating Genomic-Based Research for Health of the Institute of Medicine held a workshop in Washington, DC in February 2014. Stakeholders, including clinicians, researchers, patients, and government officials, discussed the issues related to the use of genomic information in medical practice. Assessing Genomic Sequencing Information for Health Care Decision Making is the summary of that workshop. This report compares and contrasts evidence evaluation processes for different clinical indications and discusses key challenges in the evidence evaluation process"--Publisher's description.
530 $aAlso issued online.
650 12 $aGenetic Testing.
655 2 $aCongress.
650 22 $aDiagnosis, Differential.
650 22 $aGenetics, Medical.
650 22 $aGenomics.
650 22 $aPrecision Medicine.
650 0 $aMedical genetics$xSocial aspects$vCongresses.
650 0 $aGenomics$vCongresses.
650 0 $aGenetic epidemiology$vCongresses.
650 7 $aGenetic epidemiology.$2fast$0(OCoLC)fst00940068
650 7 $aGenomics.$2fast$0(OCoLC)fst00940228
650 7 $aMedical genetics$xSocial aspects.$2fast$0(OCoLC)fst01014146
655 7 $aConference papers and proceedings.$2fast$0(OCoLC)fst01423772
700 1 $aJohnson, Samuel G.,$erapporteur.
700 1 $aOlson, Steve,$d1956-$erapporteur.
700 1 $aBerger, Adam C.,$erapporteur.
710 2 $aInstitute of Medicine (U.S.).$bRoundtable on Translating Genomic-Based Research for Health,$eissuing body.
711 2 $aAssessing Genomic Sequencing Information for Health Care Decision Making (Workshop)$d(2014 :$cWashington, D.C.)
776 08 $iAlso available in print:$aAssessing Genomic Sequencing Information for Health Care Decision Making (Workshop) (2014 : Washington, D.C.).$tAssessing genomic sequencing information for health care decision making$dWashington, D.C. : National Academies Press, 2014.$z9780309304948$z0309304946
852 00 $boff,sci$hRB155$i.A763 2014