MARC Record from marc_columbia

LEADER: 04699cam a2200733Ia 4500
001 4240972
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006 m o d
007 cr cn|||||||||
008 030402s2002 maua ob 001 0 eng d
010 $a 2001056247
035 $a(OCoLC)ocm51959878
035 $a(NNC)4240972
040 $aN$T$beng$epn$cN$T$dYDXCP$dOCLCQ$dN$T$dOCLCQ$dGBT$dTUU$dOCLCQ$dTNF$dOCLCQ$dZCU$dOCLCO$dOCLCF$dOCLCQ$dNLGGC$dOCLCQ$dAGLDB$dOCLCO$dTOA$dOCLCO$dPIFBR$dOCLCO$dOCLCQ$dWY@$dOCLCO$dOCLCA$dROC$dMNS$dOCLCO$dRCC$dOCLCO$dANT$dOCLCO$dGILDS$dVNS$dVTS$dOCLCQ$dOCLCO$dTOF$dOCLCO$dMITPR$dOCLCA$dGDC$dOCLCO$dSTF$dOCLCO$dM8D$dEBLCP$dOCLCA$dUKAHL$dUKEHC$dVT2$dOCLCO
015 $aGBA2-W7458
019 $a991947549$a1020508983$a1200075063$a1286905619
020 $a9780262270649$q(electronic bk.)
020 $a0262270641$q(electronic bk.)
020 $a0585436916$q(electronic bk.)
020 $a9780585436913$q(electronic bk.)
020 $a9780262032971
020 $a026203297X
035 $a(OCoLC)51959878$z(OCoLC)991947549$z(OCoLC)1020508983$z(OCoLC)1200075063$z(OCoLC)1286905619
037 $a3215$bMIT Press
037 $a9780262270649$bMIT Press
050 4 $aQH438.4.M3$bG46 2002eb
060 4 $aQH 438.4.M3$bG326 2002
072 7 $aSCI$x049000$2bisacsh
082 04 $a572.8/01/5118$221
049 $aZCUA
245 00 $aGene regulation and metabolism :$bpostgenomic computational approaches /$cedited by Julio Collado-Vides and Ralf Hofestädt.
260 $aCambridge, Mass. :$bMIT Press,$c©2002.
300 $a1 online resource (x, 310 pages) :$billustrations.
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
490 1 $aComputational molecular biology
504 $aIncludes bibliographical references and index.
505 0 $aAre the eyes homologous? -- Automation of protein sequence characterization and its application in whole proteome analysis -- Information fusion and metabolic network control -- Specificity of protein-DNA interactions -- Genomics of gene regulation: the view from Escherichia coli -- Discovery of DNA regulatory motifs -- Gene networks description and modeling in the GeneNet system -- Regulation of cellular states in mammalian cells from a genomewide view -- Predicting protein function and networks on a genomewide scale -- Metabolic pathways -- Toward computer simulation of the whole cell.
588 0 $aPrint version record.
520 $aAs exciting as the new field of genomics is, it has not yet produced a basic conceptual change in biology. The fundamental problems remain: the origin of life, cell organization, the pathways of differentiation, aging, and the molecular and cellular capabilities of the brain. What has occurred is an explosion of molecular information obtained by genomic sequences, which will soon be followed by exhaustive catalogs of protein interactions and protein function. This wealth of information can be analyzed and manipulated only with the help of computers. The rapidly expanding role of computers in biology may usher in a profound conceptual change in how we study living systems in the laboratory. This book focuses on current computational approaches to understanding the complex networks of metabolic and gene regulatory capabilities of the cell. The contributors look well beyond the state of the art in computational biology to anticipate what biological research will be like in a post-genomic world.
650 0 $aGenetics$xMathematical models.
650 0 $aMolecular biology$xMathematical models.
650 0 $aGenetic regulation.
650 0 $aMetabolism.
650 12 $aModels, Genetic
650 22 $aGene Expression Regulation
650 22 $aMetabolism
650 6 $aBiologie moléculaire$xModèles mathématiques.
650 6 $aRégulation génétique.
650 6 $aMétabolisme.
650 7 $ametabolism (biological concept)$2aat
650 7 $aSCIENCE$xLife Sciences$xMolecular Biology.$2bisacsh
650 7 $aGenetics$xMathematical models.$2fast$0(OCoLC)fst00940127
650 7 $aMolecular biology$xMathematical models.$2fast$0(OCoLC)fst01024743
653 $aBIOMEDICAL SCIENCES/Quantitative Biology
655 0 $aElectronic books.
655 4 $aElectronic books.
700 1 $aCollado-Vides, Julio.
700 1 $aHofestädt, Ralf.
776 08 $iPrint version:$tGene regulation and metabolism.$dCambridge, Mass. : MIT Press, ©2002$z026203297X$w(DLC) 2001056247$w(OCoLC)48383628
830 0 $aComputational molecular biology.
856 40 $uhttp://www.columbia.edu/cgi-bin/cul/resolve?clio4240972$zAll EBSCO eBooks
852 8 $blweb$hEBOOKS