MARC Record from marc_columbia

LEADER: 02619mam a2200313 a 4500
001 2119550
005 20220615210046.0
008 980319t19981998caua b 001 0 eng d
010 $a 97081368
020 $a0121413403
035 $a(OCoLC)ocm38847491
035 $9ANF7484CU
035 $a2119550
040 $aHLS$cHLS$dIXA$dAGL$dOrLoB-B
070 0 $aRS419.B86$b1998
072 0 $aX500
100 1 $aBunin, Barry A.$0http://id.loc.gov/authorities/names/nb97068785
245 14 $aThe combinatorial index /$cBarry A. Bunin.
260 $aSan Diego :$bAcademic Press,$c[1998], ©1998.
300 $axvii, 322 pages :$billustrations ;$c26 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
504 $aIncludes bibliographical references and indexes.
505 00 $g1.$tIntroduction --$g2.$tBackground --$g3.$tLinkers for Solid-Phase Synthesis --$g4.$tCombinatorial Solid-Phase Synthesis --$g5.$tAnalytical Methods for Solid-Phase Synthesis --$g6.$tPreparation of Solution Libraries and Combined Approaches at the Solution/Solid-Phase Interface --$gApp. 1.$tSummary of Functional Group Transformations for Combinatorial Solid-Phase Synthesis --$gApp. 2.$tClassification of Heterocyclization Reactions --$gApp. 3.$tUnnatural Biopolymers --$gApp. 4.$tOligosaccharides --$gApp. 5.$tList of Abbreviations.
520 $aCombinatorial chemistry has become a major focus of research activity for pharmaceutical, agrochemical, and biotechnology companies. The explosion of combinatorial methods has created the need for a compendium of reliable synthetic transformations from the primary literature. The Combinatorial Index fills this need. Included are chapters on linkers, solid-phase synthetic methods, analytical techniques, and solution libraries.
520 8 $aProcedures from the literature for constructing combinatorial libraries of small molecules comprise an indispensable laboratory reference for the synthetic chemist. Each procedure in the compilation is preceded by a section entitled "Points of Interest," which highlights the strengths and limitations of the various methods. A structural appendix covers both functional group transformations and heterocyclization reactions in solid-phase synthesis.
520 8 $aThis comprehensive but easy-to-access guide to the combinatorial chemistry literature will save time on tedious library searches, introduce a growing audience of chemists to this exciting field, and lower the barriers to attempting a new or related methodology.
650 0 $aCombinatorial chemistry$vHandbooks, manuals, etc.
852 00 $boff,che$hRS419$i.B86 1998