MARC record from Internet Archive

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245 00 $aTextbook of drug design and discovery /$c[edited by] Povl Krogsgaard-Larsen, Tommy Liljefors and Ulf Madsen.
250 $a3rd ed.
260 $aLondon ;$aNew York :$bTaylor & Francis,$c2002.
300 $axviii, 572 pages :$billustrations (some color) ;$c25 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
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500 $aRevised edition of: A textbook of drug design and development. 2nd ed. c1996.
504 $aIncludes bibliographical references and index.
505 0 $aDrug design and discovery: an overview / Lester A. Mitscher -- Role of molecular recognition in drug design / Peter Andrews and Michael Dooley -- Stereochemistry in drug design / Ian J. Kennedy and David E. Jane -- Computer-aided development and use of three-dimensional pharmacophore models / Tommy Liljefors and Ingrid Pettersson -- Quantitative structure-activity relationships and experimental design / Ulf Norinder and Thomas Högberg -- Receptors: structure, function and pharmacology / Hans Bräuner-Osborne -- Ion channels: structure, function and pharmacology / David J. Triggle -- Radiotracers: synthesis and use in imaging / Christer Halldin and Thomas Högberg -- Excitatory and inhibitory amino acid receptor ligands / Ulf Madsen and Bente Frølund -- Acetylcholine and histamine receptors and receptor ligands: medicinal chemistry and therapeutic aspects / Povl Krogsgaard-Larsen and Karla Frydenvang -- Dopamine and serotonin receptor and transporter ligands / Klaus P. Bøgesø and Benny Bang-Andersen -- Enzymes and enzyme inhibitors / Robert A. Copeland and Paul S. Anderson -- Metals in medicine: inorganic medicinal chemistry / Ole Farver -- Design and application of prodrugs / Claus S. Larsen and Jesper Østergaard -- Peptides and peptidomimetics / Kristina Luthman and Uli Hacksell -- Classical antiviral agents and design of new antiviral agents / Piet Herdewijn and Erik de Clercq -- Anticancer agents / Ingrid Kjøller Larsen and Jette Sandholm Kastrup.
520 $aThis volume provides a complete source of information on all facets of drug design. It follows drug design from the initial structure-activity relationship to the final processes of clinical evaluation and registration.
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650 7 $aQuímica farmacêutica.$2larpcal
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700 1 $aKrogsgaard-Larsen, Povl.
700 1 $aLiljefors, Tommy.
700 1 $aMadsen, Ulf.
730 0 $aTextbook of drug design and development.
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