MARC record from Internet Archive

LEADER: 07170cam 2200781Ia 4500
001 ocn476352021
003 OCoLC
005 20200508210637.0
008 091209s2010 nyua ob 001 0 eng
006 m o d
007 cr mnu||||||||
040 $aCUS$beng$epn$cCUS$dCUS$dCUV$dSCB$dGW5XE$dOCLCQ$dUBY$dOCLCA$dKIJ$dOCLCF$dVVL$dOCLCQ$dYDXCP$dEUW$dOCLCQ$dLVT$dOTZ$dOCLCA$dMERER$dOCLCQ$dU3W$dYOU$dOCLCQ$dOCLCO$dWURST$dOCLCA
019 $a771205412
020 $a9781607614166$q(Springer e-ISBN)
020 $a1607614162$q(Springer e-ISBN)
020 $z9781607614159$q(hbk.)
020 $z1607614154$q(hbk.)
035 $a(OCoLC)476352021$z(OCoLC)771205412
050 4 $aQR177
060 4 $aQZ 267
082 04 $a614.5999$223
245 00 $aMulti-drug resistance in cancer /$cedited by Jun Zhou.
260 $aNew York, N.Y. :$bHumana Press,$c℗♭2010.
300 $a1 online resource (xi, 492 pages) :$billustrations (some color)
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
490 1 $aSpringer Protocols
490 1 $aMethods in molecular biology,$x1940-6029 ;$v596
500 $aTitle from PDF title page (viewed Dec. 9, 2009).
504 $aIncludes bibliographical references and index.
505 0 $aMultidrug resistance in cancer / Bruce C. Baguley --Multidrug resistance in oncology and beyond : from imaging of drug efflux pumps to cellular drug targets / Wouter B. Nagengast [and others] -- Studying drug resistance using genetically engineered mouse models for breast cancer / Sven Rottenberg, Marina Pajic, and Jos Jonkers -- Mechanisms of multidrug resistance in cancer / Jean-Pierre Gillet and Michael M. Gottesman -- Molecular mechanisms of drug resistance in single-step and multi-step drug-selected cancer cells / Anna Maria Calcagno and Suresh V. Ambudkar -- Pharmacogenetics of ATP-binding cassette transporters and clinical implications / Ingolf Cascorbi and Sierk Haenisch -- Flow cytometric evaluation of multidrug resistance proteins / Adorjan Aszalos and Barbara J. Taylor -- Targeted chemotherapy in drug-resistant tumors, noninvasive imaging of P-glycoprotein-mediated functional transport in cancer, and emerging role of pgp in neurodagenerative [sic] diseases / Jothilingam Sivapackiam [and others] -- Epigenetic regulation of multidrug resistance 1 gene expression : profiling CpG methylation status using bisulphite sequencing / Emma K. Baker and Assam El-Osta -- Expression and function of P-glycoprotein in normal tissues : effect on pharmacokinetics / Frantisek Staud [and others] -- Molecular mechanism of ATP-dependent solute transport by multidrug resistance-associated protein 1 / Xiu-bao Chang -- Impact of breast cancer resistance protein on cancer treatment outcomes / Douglas D. Ross and Takeo Nakanishi -- Drug ratio-dependent antagonism : a new category of multidrug resistance and strategies for its circumvention / Troy O. Harasym, Barry D. Liboiron, and Lawrence D. Mayer -- Reversing agents for ATP-binding cassette drug transporters / Chow H. Lee -- Overcoming multidrug resistance in cancer : clinical studies of P-glycoprotein inhibitors / Helen M. Coley -- Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation / Jeannie M. Padowski and Gary M. Pollack -- Examination of CYP3A and P-glycoprotein-mediated drug-drug interactions using animal models / Punit H. Marathe and A. David Rodrigues -- Generating inhibitors of P-glycoprotein : where to, now? / Emily Crowley, Christopher A. McDevitt, and Richard Callaghan -- Immunosuppressors as multidrug resistance reversal agents / Hamid Morjani and Claudie Madoulet -- Overcoming multidrug resistance by RNA interference / Alexandra Stege, Andrea Kru hn, and Hermann Lage -- Circumventing tumor resistance to chemotherapy by nanotechnology / Xing-Jie Liang [and others].
520 $aWith the devastating complication of cancer cells becoming simultaneously resistant to many structurally and mechanistically unrelated drugs, the efficacy of chemotherapeutic management of cancer often becomes severely limited. In Multi-Drug Resistance in Cancer, leading researchers in the field provide comprehensive and up-to-date reviews of multidrug resistance mechanisms, from over-expression of ATP-binding cassette drug transporters such as P-glycoprotein, multidrug resistance-associated proteins, and breast cancer resistance protein, to the drug ratio-dependent antagonism and the paradigm of cancer stem cells. The extensive volume also includes strategies to overcome multidrug resistance, from the development of compounds that inhibit drug transporter function to the modulation of transporter expression, as well as techniques for detection and imaging of drug transporters, methods for investigation of drug resistance in animal models, and strategies to evaluate the efficacy of resistance reversal agents. As a volume in the highly successful Methods in Molecular Biology series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and cutting-edge, Multi-Drug Resistance in Cancer offers a state-of-art collection of reviews and methods for both basic and clinician investigators who are interested in the vital study of cancer multi-drug resistance mechanisms and reversal strategies.
650 0 $aDrug resistance in cancer cells.
650 0 $aMultidrug resistance.
650 2 $aDrug Resistance, Multiple.
650 2 $aDrug Resistance, Neoplasm.
650 2 $aNeoplasms$xdrug therapy.
650 7 $aDrug resistance in cancer cells.$2fast$0(OCoLC)fst00898703
650 7 $aMultidrug resistance.$2fast$0(OCoLC)fst01028879
653 00 $ameervoudige resistentie tegen geneesmiddelen
653 00 $amultiple drug resistance
653 00 $aneoplasms
653 00 $aoncologie
653 00 $aoncology
653 00 $alaboratoriummethoden
653 00 $alaboratory methods
653 00 $aprotocollen
653 00 $aprotocols
653 10 $aPharmacology
653 10 $aFarmacologie
655 4 $aElectronic books.
700 1 $aZhou, Jun.
776 1 $z9781607614159
830 0 $aSpringer protocols (Series)
830 0 $aMethods in molecular biology (Clifton, N.J.) ;$vv. 596.
856 40 $3SpringerLink$uhttps://doi.org/10.1007/978-1-60761-416-6$uhttp://www.springerlink.com/content/x87633/?p=7eb8d575ba00475ea17fedfd341e8a7d&pi=5
856 40 $3SpringerLink$uhttps://doi.org/10.1007/978-1-60761-416-6
856 40 $3SpringerLink$uhttp://link.springer.com/book/10.1007/978-1-60761-416-6
856 40 $3SpringerLink$uhttp://link.springer.com/10.1007/978-1-60761-416-6
856 40 $uhttps://0-link-springer-com.pugwash.lib.warwick.ac.uk/book/10.1007/978-1-60761-416-6$zConnect to Springer Protocols e-book
856 40 $uhttp://www.library.yorku.ca/e/resolver/id/2479889
856 40 $uhttp://www.library.yorku.ca/e/resolver/id/2479890
938 $aYBP Library Services$bYANK$n3149116
029 1 $aAU@$b000063338416
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994 $aZ0$bP4A
948 $hNO HOLDINGS IN P4A - 150 OTHER HOLDINGS