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001 ocn209847914
003 OCoLC
005 20200522213407.0
008 080226s2005 ne a ob 001 0 eng d
006 m o d
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020 $a9781402036422
020 $a1402036426
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024 7 $a10.1007/1-4020-3642-6$2doi
035 $a(OCoLC)209847914$z(OCoLC)62713458$z(OCoLC)228151722$z(OCoLC)228151724$z(OCoLC)228376629$z(OCoLC)317131153$z(OCoLC)437184440$z(OCoLC)516040475$z(OCoLC)607269339$z(OCoLC)647555399$z(OCoLC)698450914$z(OCoLC)756419737$z(OCoLC)814317194$z(OCoLC)823125978$z(OCoLC)824161932$z(OCoLC)880015411$z(OCoLC)957334356$z(OCoLC)992107488$z(OCoLC)994778385$z(OCoLC)1005762790$z(OCoLC)1021268042$z(OCoLC)1069505162$z(OCoLC)1073035042$z(OCoLC)1077257830$z(OCoLC)1087344743$z(OCoLC)1097255919$z(OCoLC)1097304294$z(OCoLC)1102280663$z(OCoLC)1110926479$z(OCoLC)1110946519$z(OCoLC)1112574131
037 $a978-1-4020-3641-5$bSpringer$nhttp://www.springerlink.com
050 4 $aRC269.5$b.D63 2005eb
060 4 $a2005 K-857
060 4 $aQU 58.5$bD629123 2005
072 7 $aRC$2lcco
072 7 $aSCI$x029000$2bisacsh
072 7 $aK$2bicssc
082 04 $a616.99/4$222
084 $a44.48$2bcl
084 $a44.33$2bcl
084 $aR73-37$2clc
245 00 $aDNA methylation, epigenetics, and metastasis /$cedited by Manel Esteller.
260 $aDordrecht ;$aNew York :$bSpringer,$c©2005.
300 $a1 online resource (xi, 310 pages) :$billustrations
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
347 $atext file$bPDF$2rda
490 1 $aCancer metastasis ;$vv. 7
504 $aIncludes bibliographical references.
520 1 $a"This book provides a broad and rich outline of the epigenetic mechanisms involved in cancer progression and the generation of metastasis. It describes the tumor suppressor genes undergoing transcriptional silencing by CpG island promoter hypermethylation in the different tumor types of the human anatomy and their association with tumoral behaviour. It also provides a comprehensive insightful look at the molecular players involved in DNA methylation, histone modification and chromatin remodelling complexes causing epigenetic lesions linked to the metastasic phenotypes."--Jacket.
588 0 $aPrint version record.
505 0 $aHow CpG Island Hypermethylation Leads to Cancer Dissemination: The Sounds of Silence for Tumor and Metastasis Suppressor Genes -- A Mouse Skin Multistage Carcinogenesis Model that Unmasks Epigenetic Lesions Responsible for Metastasis -- CpG Island Hypermethylation and Lung Cancer Invasion and Metastasis -- CpG Island Hypermethylation Changes During Prostate Cancer Progression and Metastasis -- CpG Island Hypermethylation in Breast Cancer Progression and Metastasis -- Epigenettic Dysregulation of Maspin (SerpinB5) in Cancer Invasion and Metastasis -- Epigenetic Regulation of the E-cadherin Cell-Cell Adhesion Gene -- Epigenetic Disruption of the SLIT-ROBO Interactions in Human Cancer -- Molecular Mechanisms of the Metastasis-Associated Gene Family of Coregulators: Role in Cancer and Invasion -- The Molecular Mechanisms for BRMS1 Action in Cancer Metastasis -- Mechanisms of DNA Demethylating Drugs Against Cancer Progression -- Histone Deacetylase Inhibitors: Novel Targeted Anti-Cancer Agents.
650 0 $aMetastasis.
650 0 $aMethylation.
650 2 $aDNA Methylation.
650 2 $aEpigenesis, Genetic.
650 2 $aMethylation.
650 2 $aGenetic Phenomena.
650 2 $aNeoplastic Processes.
650 2 $aGene Expression Regulation.
650 2 $aAlkylation.
650 2 $aNeoplasms.
650 2 $aPathologic Processes.
650 2 $aChemical Phenomena.
650 2 $aBiochemical Phenomena.
650 2 $aDisease.
650 2 $aMetabolism.
650 2 $aPathological Conditions, Signs and Symptoms
650 2 $aPhenomena and Processes
650 2 $aNeoplasm Metastasis.
650 24 $aOncology.
650 24 $aMolecular Medicine.
650 24 $aCancer Research.
650 24 $aBiotechnology.
650 24 $aBiomedicine general.
650 24 $aBiochemistry, general.
650 14 $aBiomedicine.
650 7 $aSCIENCE$xLife Sciences$xGenetics & Genomics.$2bisacsh
650 07 $aEpigenesis.$2cct
650 07 $aMetastasis.$2cct
650 07 $aDNA$xMethylation.$2cct
650 7 $aBiomédecine.$2eclas
650 7 $aSciences de la vie.$2eclas
650 7 $aMetastasis.$2fast$0(OCoLC)fst01018329
650 7 $aMethylation.$2fast$0(OCoLC)fst01018765
655 0 $aElectronic books.
655 4 $aElectronic books.
700 1 $aEsteller, Manel.
773 0 $tSpringer e-books
776 08 $iPrint version:$tDNA methylation, epigenetics, and metastasis.$dDordrecht ; New York : Springer, ©2005$z1402036418$z9781402036415$w(DLC) 2005282696$w(OCoLC)61180768
830 0 $aCancer metastasis (Series) ;$vv. 7.
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