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LEADER: 05377cam 2200889 a 4500
001 ocm30545966
003 OCoLC
005 20200518021417.0
008 940512s1994 nyua b 001 0 eng
010 $a 94019184
040 $aDNLM/DLC$beng$cDLC$dNLM$dWSM$dUKM$dAGL$dUBA$dOCLCQ$dBAKER$dNLGGC$dBTCTA$dYDXCP$dOCLCQ$dZWZ$dOCLCF$dOCLCQ$dOCLCO$dOCLCQ$dT9K$dCAI$dOCLCO$dUKMGB$dUWO$dOCLCA$dUKUOY
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019 $a1027873207
020 $a047102189X$q(alk. paper)
020 $a9780471021896$q(alk. paper)
035 $a(OCoLC)30545966$z(OCoLC)1027873207
050 00 $aQH573$b.M63 vol. 15$aQP551
060 00 $aW1$bMO124T v.15 1994
060 10 $aQU 55$bC3929 1994
070 0 $aQH573.M6$bv.15
072 0 $aX300
082 00 $a574.87 s$a574.19/245$220
084 $a42.15$2bcl
245 00 $aCellular proteolytic systems /$ceditors, Aaron J. Ciechanover, Alan L. Schwartz.
260 $aNew York :$bWiley-Liss,$c℗♭1994.
300 $ax, 233 pages :$billustrations ;$c26 cm.
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
338 $avolume$bnc$2rdacarrier
490 1 $aModern cell biology ;$vv. 15
504 $aIncludes bibliographical references and index.
505 0 $aPreface / Aaron J. Ciechanover and Alan L. Schwartz -- The Ubiquitin-Mediated Proteolytic Pathway: Mechanisms of Recognition of the Proteolytic Substrate and Involvement in the Degradation of Native Cellular Proteins / Aaron J. Ciechanover and Alan L. Schwartz -- Molecular Genetics of the Ubiquitin System / David Keith Gonda -- Selective Degradation of Cytosolic Proteins by Lysosomes / J. Fred Dice and Stanley R. Terlecky -- Autophagy: Its Mechanism and Regulation / Glenn E. Mortimore and Motoni Kadowaki -- Hepatic Endosomes Are a Major Physiological Locus of Insulin and Glucagon Degradation In Vivo / Francois Authier, Barry I. Posner and John J. M. Bergeron -- Proteolysis in the Yeast Vacuole / Elizabeth W. Jones and Deborah G. Murdock -- Degradation of Proteins Retained in the Endoplasmic Reticulum / Juan S. Bonifacino and Richard D. Klausner -- Protein Catabolism and Antigen Processing / Clifford V. Harding -- Viral Proteases: Structure and Function / Tudor I. Oprea, Chris L. Waller and Garland R. Marshall.
520 $aWithin cells, regulation of protein degradation, or proteolysis, is critical to dynamic control of protein levels. Cellular Proteolytic Systems is the first book to provide a detailed and comprehensive summary of advances in the biochemistry, cellular biology, molecular genetics, and physiology of the major proteolytic processes. The field of cellular proteolysis is advancing rapidly and has great potential impact in a variety of research and clinical areas, including AIDS and cancer research and treatment. The editors, pioneers in the field of cellular and protein research, describe our current understanding of the three major cellular proteolytic systems: the ubiquitin system, the lysosomal and vacuolar systems, and physiological and pathophysiological cellular proteolysis. Individual chapters cover topics from the molecular genetics of the ubiquitin system to regulation of autophagy to antigen processing and presentation. Cellular Proteolytic Systems will provide an excellent foundation in the biological basis of protein turnover for cellular, developmental, and molecular biologists.
583 1 $aFinite$c2018$5UoY
650 0 $aProteins$xMetabolism.
650 0 $aProteolytic enzymes.
650 0 $aLysosomes.
650 0 $aUbiquitin.
650 7 $aUbiquitines$xPhysiologie.$2fmesh
650 7 $aLysosomes$xPhysiologie.$2fmesh
650 7 $aProte ines$xPhysiologie.$2fmesh
650 7 $aLysosomes.$2fast$0(OCoLC)fst01004402
650 7 $aProteins$xMetabolism.$2fast$0(OCoLC)fst01079741
650 7 $aProteolytic enzymes.$2fast$0(OCoLC)fst01079783
650 7 $aUbiquitin.$2fast$0(OCoLC)fst01160282
650 7 $aProteinas (metabolismo)$2larpcal
650 7 $aBiologia molecular e macromolecular.$2larpcal
650 7 $aPeptidases.$2ram
650 7 $aProte ines$xMe tabolisme.$2ram
650 7 $aLysosomes.$2ram
650 12 $aProteins$xmetabolism.
650 22 $aLysosomes$xphysiology.
650 22 $aUbiquitins$xphysiology.
650 6 $aProte ines$xMe tabolisme.
650 6 $aEnzymes prote olytiques.
650 6 $aUbiquitine.
653 0 $aProteins$aMetabolism
700 1 $aCiechanover, Aaron J.
700 1 $aSchwartz, Alan L.
776 08 $iOnline version:$tCellular proteolytic systems.$dNew York : Wiley-Liss, ℗♭1994$w(OCoLC)624807116
830 0 $aModern cell biology ;$vv. 15.
856 41 $3Table of contents$uhttp://catdir.loc.gov/catdir/toc/onix03/94019184.html
856 42 $3Publisher description$uhttp://catdir.loc.gov/catdir/description/wiley037/94019184.html
938 $aBaker & Taylor$bBKTY$c199.00$d199.00$i047102189X$n0002511391$sactive
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938 $aYBP Library Services$bYANK$n413842
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029 1 $aUKMGB$b009741760
029 1 $aUKMGB$b006240072
994 $aZ0$bP4A
948 $hNO HOLDINGS IN P4A - 186 OTHER HOLDINGS