MARC Record from harvard_bibliographic_metadata

LEADER: 04438cam a22005538i 4500
001 014052754-0
005 20140610225215.0
008 130530s2014 enk b 001 0 eng
010 $a 2013020914
016 7 $a101618838$2DNLM
020 $a9780199316410 (hardback)
020 $a0199316414
035 $a(PromptCat)99958589568
035 0 $aocn839396637
040 $aDLC$beng$erda$cDLC$dBTCTA$dOCLCO$dOCLCA$dYDXCP$dIUL$dCUS$dOCLCF$dNLM$dVP@$dNSB$dLMR$dVVX
042 $apcc
050 00 $aRB155$b.D36 2014
060 00 $a2013 I-859
060 10 $aQW 541
082 00 $a616/.042$223
084 $aMED044000$2bisacsh
100 1 $aDavis, Daniel M.$q(Daniel Michael),$d1970-$eauthor.
245 14 $aThe compatibility gene :$bhow our bodies fight disease, attract others, and define our selves /$cDaniel M. Davis.
264 1 $aOxford :$bOxford University Press,$c[2014]
300 $axvi, 231 pages ;$c25 cm
336 $atext$2rdacontent
337 $aunmediated$2rdamedia
338 $avolume$2rdacarrier
504 $aIncludes bibliographical references and index.
505 0 $aThe Scientific Revolution in Compatibility: Frankenstein's holy trinity ; Self / non-self ; Dead but alive in parts ; A crystal-clear answer at last. -- The Frontier of Compatibility Gene Research: Differences between us that matter ; A path to new medicine ; Missing self. -- The Overarching System: Sex and smelly T-shirts ; Connections with the mind ; Compatibility for successful pregnancy. -- What makes you so special?
520 $aThis work takes readers on a global journey of discovery spanning 60 years, involving scores of scientists, and encompassing the history of transplants and immunology. That journey has revealed astonishing links between who we are as individuals and our never-ceasing struggle to survive disease. Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease. In this book the author, an immunologist draws on new research to suggest a number of even more fascinating, and controversial, conclusions about compatibility genes: that we find others more or less sexy according to their compatibility genes (dating services are starting to match people in this way); that the wiring between some neurons is kept or broken according to the activity of compatibility genes; and that compatibility genes influence the chances of a couple having a successful pregnancy. Profoundly personal, life-forming and life-changing decisions appear to be governed by the actions of a few inherited genes. Most importantly, the author proposes that because we each respond slightly differently to any particular disease, in the not-too-distant future vaccines and other medications may be tailored to match our compatibility genes, a revolutionary breakthrough in the fight against disease. Including vivid portraits of the scientists who worked tirelessly to unlock the secrets of compatibility genes, as well as patients who survived disease due to lucky genetic inheritances, this book explains an aspect of human biology that will undoubtedly have profound impacts on medical practice in the 21st Century. -- Provided by publisher.
520 $a"There are far-reaching consequences from the way our body has evolved to fight disease. This book describes how genes link our struggle with disease to compatibility with others, the wiring of our brain and success in pregnancy"--$cProvided by publisher.
650 0 $aMedical genetics.
650 0 $aInfection$xImmunological aspects.
650 0 $aImmunogenetics.
650 0 $aHuman molecular genetics.
650 7 $aMEDICAL / Immunology.$2bisacsh
650 7 $aHuman molecular genetics.$2fast$0(OCoLC)fst00963180
650 7 $aImmunogenetics.$2fast$0(OCoLC)fst00967949
650 7 $aInfection$xImmunological aspects.$2fast$0(OCoLC)fst00972331
650 7 $aMedical genetics.$2fast$0(OCoLC)fst01014133
650 12 $aImmunogenetic Phenomena.
650 22 $aAutoimmune Diseases$xgenetics.
650 22 $aImmune System Processes.
650 22 $aImmunological Synapses.
650 22 $aTransplantation Immunology$xgenetics.
899 $a415_565553
988 $a20140515
906 $0DLC