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LEADER: 05739pam a2200457 a 4500
001 012508917-1
005 20100712192110.0
008 100616s2010 ne a b 001 0 eng
010 $a 2009941948
015 $aGBA982747$2bnb
020 $a9789048132706 (alk. paper)
020 $a9048132703 (alk. paper)
020 $a9789048132713 (e-ISBN)
020 $a9048132711 (e-ISBN)
035 0 $aocn682004975
035 0 $aocn620034685
040 $aUKM$cUKM
041 0 $aeng
042 $aukblcatcopy$anlmcopyc
050 00 $aQP188.P26$bI85 2010
060 00 $aW1$bAD599 v.654 2010
060 10 $aWK 800$bI818 2010
245 04 $aThe islets of Langerhans /$cMd. Shahidul Islam, editor.
260 $aDordrecht ;$aLondon :$bSpringer,$cc2010.
300 $axix, 798 p. :$bill.
490 1 $aAdvances in experimental medicine and biology,$x0065-2598 ;$v654
504 $aIncludes bibliographical references and index.
505 0 $aMicroscopic anatomy of the human islet of Langerhans / P. In't Veld and M. Marichal -- The comparative anatomy of islets / R.S. Heller -- Approaches for imaging islets: recent advances and future prospects / U. Ahlgren and M. Gotthardt -- Islet cell development / A. Rojas [and others] -- High fat programming of beta-cell failure / M.E. Cerf -- Nutrient regulation of insulin secretion and beta-cell functional integrity / P. Newsholme, C. Gaudel and N.H. McClenaghan -- Electrophysiology of islet cells / G. Drews, P. Krippeit-Drews and M. Dufer -- ATP-sensitive potassium channels in health and disease / R. Clark and P. Proks -- Role of mitochondria in beta-cell function and dysfunction / P. Maechler [and others] -- Basement membrane in pancreatic islet function / M. Kragl and E. Lammert -- Calcium signaling in the islets / M.S. Islam -- Electrical bursting, calcium oscillations, and synchronization of pancreatic islets / R. Bertram, A. Sherman and L.S. Satin --
505 0 $aCyclic AMP signaling in pancreatic islets / B. Furman, W.K. Ong and N.J. Pyne -- Exocytosis in islet beta-cells / H. Kasai [and others] -- The novel roles of glucagon-like peptide-1, angiotensin II, and vitamin D in islet function / P.S. Leung and Q. Cheng -- Proteomics and islet research / M. Ahmed -- Wnt signaling in pancreatic islets / Z. Liu and J.F. Habener -- Molecular pathways underlying the pathogenesis of pancreatic alpha-cell dysfunction / D. Kawamori, H.J. Welters and R.N. Kulkarni -- Mechanisms of pancreatic beta-cell apoptosis in diabetes and its therapies / J.D. Johnson and D.S. Luciani -- beta-cell function in obese-hyperglycemic mice [ob/ob Mice] / P. Lindstrom -- Islet structure and function in the GK rat / B. Portha [and others] -- The beta-cell in human type 2 diabetes / P. Marchetti [and others] -- Clinical approaches to preserve beta-cell function in diabetes / B.L. Wajchenberg -- Immunology of beta-cell destruction / D. La Torre and A. Lernmark --
505 0 $aToll-like receptors and type 1 diabetes / D. Zipris -- Prevention of beta-cell destruction in autoimmune diabetes: current approaches and future prospects / S.K. Sedimbi and C.B. Sanjeevi -- In vivo regeneration of insulin-producing beta-cells / H.S. Jun -- Customized cell-based treatment options to combat autoimmunity and restore beta-cell function in type 1 diabetes mellitus: current protocols and future perspectives / F. Fandrich and H. Ungefroren -- The programmable cell of monocytic origin (PCMO): a potential adult stem/progenitor cell source for the generation of islet cells / H. Ungefroren and F. Fandrich -- Islet isolation for clinical transplantation / T. Kin -- Human islet autotransplantation: the trail thus far and the highway ahead / M. Hermann, R. Margreiter and P. Hengster -- Modulation of early inflammatory reactions to promote engraftment and function of transplanted pancreatic islets in autoimmune diabetes / L. Piemonti, L.G. Guidotti and M. Battaglia --
505 0 $aSuccesses and disappointments with clinical islet transplantation / P. Cravedi [and others] -- Islet cell tumours / S. Ekeblad.
520 $a'This book is a unique and thoughtful blend of critical background information and advances made in a multitude of areas of contemporary islet research. It is an essential reference book, the first of its kind in many years, for professionals as well as for the beginners interested in the study of islet physiology and diabetes. The book is unique in its breadth: it deals with anatomy, histology, ultra-structure, evolution and comparative anatomy, imaging, developmental biology, programming, apoptosis, mitochondrial function, metabolism, cellular signaling, electrophysiology, oscillation of hormone secretion, islets of model animals, immunology, proteomics, regenerative medicine, clinical advances, islet transplantation, and finally islet tumors. Individual chapters contributed by over a hundred experts and enthusiasts, not only provide a balanced view of the recent advances made in the respective fields, but also provide directions and thoughts for future research. Thanks to vivid and colorful illustrations, tables and sketches, the book as a whole, and the individual chapters make reading a pleasant experience. It is a valuable compilation that one would love to possess personally and buy as a present to a colleague.'--From books.google.com.hk.
650 22 $aIslets of Langerhans Transplantation.
650 12 $aIslets of Langerhans.
650 0 $aIslands of Langerhans$xPathophysiology.
650 0 $aIslands of Langerhans$xMolecular aspects.
700 1 $aIslam, Md. Shahidul,$cM.D.
700 1 $aIslam, Md. Shahidul,$d1956-
830 0 $aAdvances in experimental medicine and biology ;$vv. 654.
988 $a20100616
906 $0OCLC