MARC Record from harvard_bibliographic_metadata

LEADER: 03308cam a22003854a 4500
001 011472449-0
005 20080522134323.0
008 071010s2007 nyua b 001 0 eng
010 $a 2007042192
016 7 $a101318411$2DNLM
020 $a9780387767147
020 $a0387767142
035 0 $aocn175174340
040 $aDNLM/DLC$cDLC$dYDX$dNLM$dYDXCP$dBAKER$dIXA
042 $apcc
050 00 $aQP363$b.A92 2007
060 00 $aW1$bAD559 v.621 2007
060 10 $aWL 102.5$bA9703 2007
082 00 $a612.8$222
245 00 $aAxon growth and guidance /$cedited by Dominique Bagnard.
260 $aNew York :$bSpringer Science + Business Media ;$aAustin, Tex. :$bLandes Bioscience,$cc2007.
300 $axvi, 169 p. :$bill. (some col.) ;$c26 cm.
440 0 $aAdvances in experimental medicine and biology ;$vv. 621
504 $aIncludes bibliographical references and index.
505 0 $aMolecular mechanisms of axonal growth / Céline Bouquet and Fatiha Nothias -- Netrins and their receptors / Simon W. Moore, Marc Tessier-Lavigne and Timothy E. Kennedy -- EPH receptors and ephrin ligands in axon guidance / Michael Reber, Robert Hindges, and Greg Lemke -- Role of semaphorins during axon growth and guidance / Eric Koncina ... [et al.] -- Slits and their receptors / Alain Chédotal -- Neurotrophic factors: are they axon guidance molecules? / Sarah Guthrie -- The role of cell adhesion molecules in axon growth and guidance / Hiroyuki Kamiguchi -- Neurotransmitters and the development of neuronal circuits / Tina Ruediger and Juergen Bolz -- The hedgehog, TGF-b/BMP, and Wnt families of morphogens in axon guidance / Frédéric Charron and Marc Tessier-Lavigne -- The role of cyclic nucleotides in axon guidance / Michael Piper, Francis van Horck and Christine Holt -- Membrane lipid rafts and their role in axon guidance / Carmine Guirland and James Q. Zheng -- The role of glial cells in axon guidance, fasciculation, and targeting / Anabel R. Learte and Alicia Hidalgo.
520 $aThis book proposes an updated view of the current knowledge of the molecular and cellular mechanisms ensuring axon growth and guidance. The introductory chapter will remind the readers of all the features of a growth cone and the mechanisms controlling its growth. From there, one enters a fabulous journey with a growth cone, a Tom Thumb story filled with molecular encounters and complex interactions leading to one of the most fantastic developmental achievements: the nervous system wiring. The journey starts with a description of the classical guidance signals such as the netrins, the semaphorins, the ephrins or the Slit family. The question of the exact definition of a guidance signal is addressed in a chapter which discusses whether neurotrophic factors can be considered as guidance cues. This complex question is also considered in a chapter presenting the role of adhesion molecules during axon guidance and the report of compelling evidence for a guidance effect of neurotra.
650 0 $aAxons$xPhysiology.
650 0 $aNervous system$xRegeneration.
650 0 $aNervous system$xGrowth.
650 12 $aAxons$xphysiology.
650 22 $aNerve Regeneration.
650 22 $aNervous System$xgrowth & development.
700 1 $aBagnard, Dominique.
988 $a20080522
906 $0OCLC