MicroRNAs in development and cancer

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MicroRNAs in development and cancer
Frank J. Slack
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Last edited by MARC Bot
October 12, 2020 | History

MicroRNAs in development and cancer

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"MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represent a paradigm shift in thinking about gene regulation during development and disease, and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer."--Back cover.

Publish Date
Language
English
Pages
282

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Edition Availability
Cover of: MicroRNAs in development and cancer
MicroRNAs in development and cancer
2011, Imperial College Press, World Scientific [distributor]
in English
Cover of: Micrornas in Development and Cancer
Micrornas in Development and Cancer
2010, Imperial College Press
in English

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Book Details


Published in

London, Hackensack, NJ

Table of Contents

Introduction to gene regulation by small RNAs
The emerging non-coding RNA world
MicroRNAs in C. elegans development
MicroRNAs in mammalian development
MicroRNAs in hematopoietic development
MicroRNAs function as tumor suppressor genes and oncogenes
Simultaneous detection of primary, precursor and mature microRNAs by qPCR
Single nucleotide polymorphisms in microRNAs and microRNA binding sites with roles in cancer
MicroRNAs as potential diagnostics and therapeutics
MicroRNA target prediction
Non-coding RNAs in cancer: the other part of the story.

Edition Notes

Includes bibliographical references and index.

Series
Molecular medicine and medicinal chemistry -- v. 1, Molecular medicine and medicinal chemistry -- v. 1

Classifications

Dewey Decimal Class
616.992
Library of Congress
QP623.5.S63 .M532 2011,

The Physical Object

Pagination
xv, 282 p. :
Number of pages
282

ID Numbers

Open Library
OL25369489M
ISBN 10
1848163665
ISBN 13
9781848163669
LCCN
2012419322
OCLC/WorldCat
298781535

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History

Download catalog record: RDF / JSON / OPDS | Wikipedia citation
October 12, 2020 Edited by MARC Bot import existing book
October 9, 2020 Edited by ImportBot import existing book
August 1, 2020 Edited by ImportBot import existing book
July 4, 2012 Created by LC Bot Imported from Library of Congress MARC record.