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Toxicology Handbook, 2nd Edition |
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Murray, Daly, McCoubrie, Soderstrom, Pascu, Armstrong & Cadogan |
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Table of Contents |
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Section 1: Introduction |
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Who are the authors |
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Scope of the book |
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Handbook of acute management of common poisonings. |
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Hands on and practical approach. |
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Rationale for drugs included |
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How to use the book |
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Universal disclaimer |
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Clinical: Approach to the poisoned patient |
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Overview of approach to toxicology/toxinology |
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Principles of risk assessment-based approach |
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Resuscitation, Risk assessment, Supportive care, Decontamination, Investigations, Enhanced elimination, Antidotes, Disposition |
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Section 2: Approach to specialist toxicology problems |
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Approach to special problems: Approach to snakebite, mushroom poisoning, plant poisoning |
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Toxidromes: Serotonin syndrome, Neuroleptic Malignant Syndrome, anticholinergic syndrome, cholinergic syndrome |
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Important poisoning manifestations and management: Seizures, coma, hypotension, delirium and agitation |
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Drugs of abuse and withdrawal syndromes: Alcohol, amphetamines, opiods, sedative hypnotics, body packers and stuffers |
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Investigations: Laboratory results: acidosis, anion gap and osmolar gap, recommended baseline investigations with interpretation. Unit conversion table: ECG interpretation in poisoning: Radiology. |
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Special populations: Paediatric poisoning: 1 tablet can kill (list), special precautions in management (overnight stay, paracetamol, risk of charcoal etc); Pregnancy and lactation and poisoning; and Geriatric poisoning |
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Section 3: Toxic Drugs (78 chapters) |
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Approach to diagnosis, investigation and management of the poisoned patient with all of the common drug presentations. Updated with 8 new drug chapters as per readers nominations and feedback |
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Section 4: Antidotes (29 chapters) |
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Detailed description of indications, contraindications, clinical administration and therapeutic end-points for all antidotes. New chapter on Intralipid, the latest development in antidote therapy |
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Section 5: Toxinology (16 chapters) |
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Approach to snakebite, spider and marine envenoming. New chapter on tick envenoming |
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Section 6: Antivenom (11 chapters) |
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Detailed description of indications, contraindications, clinical administration and therapeutic end-points for all antivenoms |
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Appendices Sample ECGs from poisoned patients; Drug concentrations and unit conversion chart; Guide to the management of allergic reaction to antivenom |
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