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October 22, 2010 | History

Natural product chemistry for drug discovery 1 edition

Natural product chemistry for drug discovery
Antony D. Buss



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Natural product chemistry for drug discovery
edited by Antony D. Buss and Mark S. Butler

Published 2010 by Royal Society of Chemistry in Cambridge .
Written in English.

Table of Contents

Natural products as drugs and leads to drugs: The historical perspective / David J. Newman and Gordon M. Cragg
Chemical space and the difference between natural products and synthetics / Sheo B. Singh and J. Chris Culberson
Mechanism of action studies / James J. La Clair
The convention on biological diversity and its impact on natural product research / Geoffrey A. Cordell
Plants: Revamping the oldest source of medicines with modern science / Giovanni Appendino and Federica Pollastro
Macromarines: A selective account of the potential of marine sponges, molluscs, soft corals and tunicates as a source of therapeutically important molecular structures / Jennifer Carroll and Phillip Crews
Microorganisms: Their role in the discovery and development of medicines / Cedric Pearce, Peter Eckard, Iris Gruen-Wollny and Friedrich G. Hansske
Advances in biological screening for lead discovery / Christian N. Parker, Johannes Ottl, Daniela Gabriel and Ji-Hu Zhang
Advances in instrumentation, automation, dereplication and prefractionation / Tim S. Bugni, Mary Kay Harper, Malcolm W.B. McCulloch and Emily L. Whitson
Natural product combinatorial biosynthesis: Promises and realities / Daniel W. Udwary
A snapshot of natural product-derived compounds in late stage clinical development at the end of 2008 / Mark S. Butler
From natural product to clinical trials: NPI-0052 (Salinosporamide A), a marine actinomycete-derived
anticancer agent / Kin S. Lam, G. Kenneth Lloyd, Saskia T. C. Neuteboom, Michael A. Palladino, Kobi M. Sethna, Matthew A. Spear and Barbara C. Potts
From natural product to clinical trials: Bevirimat, a plant-derived anti-AIDS drug / Keduo Qian, Theodore J. Nitz, Donglei Yu, Graham P. Allaway, Susan L. Morris-Natschke and Kuo-Hsiung Lee
Daptomycin / Richard H. Baltz
Micafungin / Akihiko Fujie, Shuichi Tawara and Seiji Hashimoto.

Edition Notes

Includes bibliographical references and index.

Biomolecular sciences


Dewey Decimal Class
Library of Congress
RS160 .N375 2010

The Physical Object

xvii, 440 p. :
Number of pages

ID Numbers

Open Library
Internet Archive
LC Control Number

History Created October 22, 2010 · 1 revision Download catalog record: RDF / JSON

October 22, 2010 Created by ImportBot initial import