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January 24, 2010 | History

Relationship between sleep apnea syndrome and the risk of death in chronic end-stage renal disease patients treated by renal replacement therapy 1 edition

Relationship between sleep apnea syndrome and the risk of death in chr ...
Andre Charest

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Relationship between sleep apnea syndrome and the risk of death in chronic end-stage renal disease patients treated by renal replacement therapy
a pilot study.

Published 2005 .
Written in English.

About the Book

Sleep apnea (SA) is associated with an increased risk of cardiovascular outcomes in the general population. SA seems more prevalent in end-stage renal disease (ESRD) patients and may in part explain their higher risk of cardiovascular events. In a historical cohort study of 65 ESRD patients on chronic dialysis we studied the relationship between apnea-hypopnea index (AHI) and mortality and asked whether SA, traditionally defined as an AHI of 15 events per hour of sleep or more, increased the risk of death. SA was present in 63% of subjects; they were older (p=0.007), heavier (body mass index 27.9 +/- 6.2 kg/m 2) (p=0.0005), sicker (Charlson co-morbidity index) (p=0.03) and more likely to have diabetes causing ESRD (p=0.005). In multivariate analysis, only age (p=0.04) and baseline AHI (hazard ratio 1.33/15 units of AHI; 95% CI: 1.05--1.68; p=0.02) were significantly associated with mortality. Further studies are warranted to confirm those results.

Edition Notes

Source: Masters Abstracts International, Volume: 44-02, page: 0834.

Thesis (M.Sc.)--University of Toronto, 2005.

Electronic version licensed for access by U. of T. users.

GERSTEIN MICROTEXT copy on microfiche (2 microfiches).

The Physical Object

Pagination
115 leaves.
Number of pages
115

ID Numbers

Open Library
OL19217685M
ISBN 10
0494074744

History Created December 11, 2009 · 2 revisions Download catalog record: RDF / JSON

January 24, 2010 Edited by WorkBot add more information to works
December 11, 2009 Created by WorkBot add works page