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January 24, 2010 | History

Is seizure onset related to visual deficits seen in pediatric epilepsy patients exposed to vigabatrin and can a visual evoked potential be used to follow vigabatrin therapy in this group? 1 edition

Is seizure onset related to visual deficits seen in pediatric epilepsy ...
Sivan Bega

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Is seizure onset related to visual deficits seen in pediatric epilepsy patients exposed to vigabatrin and can a visual evoked potential be used to follow vigabatrin therapy in this group?

Published 2005 .
Written in English.

About the Book

Children with infantile spasms have reduced visual functions such as contrast sensitivity and grating acuity. The sweep visual evoked potential was used to determine the basis for these deficits. All children tested had been exposed to vigabatrin, an anti epileptic drug. Subjects were divided into two groups: those who have infantile spasms correlated with an EEG pattern of hypsarrhythmia, and those with other seizure disorders. Both groups showed visual deficits compared with controls. In the infantile spasms group, neither seizure onset nor current vigabatrin therapy were related to visual deficits. In the other seizure group, later seizure onset and discontinuation of vigabatrin at test date were correlated with less severe deficits. We conclude that visual deficits seen in children with infantile spasms may be correlated with the presence of hypsarrhythmia. Children with other seizure disorders have deficits associated with age at seizure onset and the retinal effects of vigabatrin.

Edition Notes

Source: Masters Abstracts International, Volume: 44-02, page: 0768.

Thesis (M.Sc.)--University of Toronto, 2005.

Electronic version licensed for access by U. of T. users.

GERSTEIN MICROTEXT copy on microfiche (2 microfiches).

The Physical Object

Pagination
124 leaves.
Number of pages
124

ID Numbers

Open Library
OL19217437M
ISBN 10
0494074221

History Created December 11, 2009 · 2 revisions Download catalog record: RDF / JSON

January 24, 2010 Edited by WorkBot add more information to works
December 11, 2009 Created by WorkBot add works page